PMP70 Antibody

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Rat.

We have publications tested in 1 application: WB.

Showing Publications 1 - 2 of 2.

Publications using NBP1-20871	Applications	Species
Panov AV, Kubalik N, Zinchenko N et al. Metabolic and functional differences between brain and spinal cord mitochondria underlie different predisposition to pathology Am J Physiol Regul Integr Comp Physiol 2011-04-01 [PMID: 21248309] (WB, Rat)	WB	Rat
Liu LX, Janvier K, Berteaux-Lecellier V et al. Homo- and heterodimerization of peroxisomal ATP-binding cassette half-transporters. J Biol Chem 1999-11-12 [PMID: 10551832]

Array NBP1-20871

• PMP70 Antibodies
• PMP70 Proteins