PMP70 Products

Description

PMP70 is encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Bioinformatics

Entrez	19299 Mouse 25270 Rat 5825 Human
Uniprot	AAH09712 Human NP_002849 Human NP_002849.1 Human P16970 Rat P28288 Human P55096 Mouse
Product By Gene ID	5825
Alternate Names	70 kDa peroxisomal membrane protein ABC43 ATP-binding cassette, sub-family D (ALD), member 3 peroxisomal membrane protein 1 (70kD, Zellweger syndrome) Peroxisomal membrane protein-1 (70kD) PMP70ATP-binding cassette sub-family D member 3 PXMP1dJ824O18.1 (ATP-binding cassette, sub-family D (ALD), member 3 (PMP70, PXMP1)) ZWS2

Research Areas for PMP70

Find related products by research area and learn more about each of the different research areas below.

ABC Transporters
Cellular Markers
Lipid and Metabolism
Neuroscience
Peroxisome Markers
Signal Transduction