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PEX14 Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: PEX14 Antibody [NBP2-33455] - Staining of human cell line U-2 OS shows localization to peroxisomes. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: PEX14 Antibody [NBP2-33455] - Staining of human gastrointestinal shows strong cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: PEX14 Antibody [NBP2-33455] - Staining of human fallopian tube shows strong cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: PEX14 Antibody [NBP2-33455] - Staining of human liver shows moderate cytoplasmic granular positivity in hepatocytes.
Immunohistochemistry-Paraffin: PEX14 Antibody [NBP2-33455] - Staining of human prostate shows strong cytoplasmic positivity in glandular cells.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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PEX14 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: IQQQQKIQELAHELAAAKATTSTNWILESQNINELKSEINSLKGLLLNRRQFPPSPSAPKIPSWQIPVKSPSPSSP
Predicted Species
Mouse (95%), Rat (97%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PEX14
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
PEX14 Protein (NBP2-33455PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for PEX14 Antibody

  • dJ734G22.2
  • MGC12767
  • NAPP2
  • NF-E2 associated polypeptide 2
  • peroxin-14
  • peroxisomal biogenesis factor 14
  • Peroxisomal membrane anchor protein PEX14
  • peroxisomal membrane anchor protein Pex14p
  • peroxisomal membrane protein PEX14
  • Pex14p
  • PTS1 receptor docking protein
  • PTS1 receptor-docking protein

Background

PEX14 encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

ICC/IF Video Protocol

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Bioinformatics

Gene Symbol PEX14
Uniprot