Plectin Antibody Summary
Immunogen |
Between 4534 and 4684 |
Standard Curve Range |
[Standard Curve Range] |
Sensitivity |
[Sensitivity] |
Assay Type |
[Assay Type] |
Sample Volume |
[Sample Volume] |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
PLEC |
Purity |
Affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Store at 4C. Do not freeze. |
Buffer |
Tris-citrate/phosphate buffer, pH 7 to 8 |
Preservative |
0.09% Sodium Azide |
Purity |
Affinity purified |
Alternate Names for Plectin Antibody
Background
Plectin, a 500-kDa intermediate filament binding protein, is localized to the cytoplasm and acts to both stabilize and give strength to cells via cross-linking (1). Plectin cross-links intermediate filaments to microtubules and microfilaments, and anchors intermediate filaments to the plasma and nuclear membranes (2,3). Plectin binds many proteins, including actin, vimentin, and Lamin B. Phosphorylation by PKA or PKC results in decreased binding to Lamin B, and phosphorylation by PKA enhances the plectin-vimentin interactions (4).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Product General Protocols
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Video Protocols
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Secondary Antibodies
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