Reactivity | MuSpecies Glossary |
Applications | WB |
Clone | 120304 |
Clonality | Monoclonal |
Host | Rat |
Conjugate | Unconjugated |
Immunogen | E. coli-derived recombinant mouse Plasminogen Kringle 5 Cys481-Ala563 Accession # AAA50168 |
Specificity | Detects mouse Plasminogen Kringle 5 in direct ELISAs and Western blots. In direct ELISAs, no cross‑reactivity with recombinant human Plasminogen Kringle 5 is observed. |
Source | N/A |
Isotype | IgG1 |
Clonality | Monoclonal |
Host | Rat |
Gene | Plg |
Purity Statement | Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Publications |
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Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
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Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
Preservative | No Preservative |
Reconstitution Instructions | Reconstitute at 0.5 mg/mL in sterile PBS. |
Plasminogen is a coenzyme that has five triple disulfide-linked kringle domains. It is converted to plasmin by plasminogen activators. Internal fragments of plasminogen, including the naturally occurring angiostatin isoforms and Kringle 5, can also be generated by proteolytic cleavage. These internal fragments have been shown to be potent angiogenesis inhibitors (1).
Publication using MAB742 | Applications | Species |
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Das R, Burke T, Plow EF Histone H2B as a functionally important plasminogen receptor on macrophages. Blood, 2007-08-09;110(10):3763-72. 2007-08-09 [PMID: 17690254] (ICC, Mouse) | ICC | Mouse |
Secondary Antibodies |
Isotype Controls |
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