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Paxillin Antibody (LD4 sAB) [mFluor Violet 450 SE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF
Clone
LD4 sAB
Clonality
Monoclonal
Host
Rabbit
Conjugate
mFluor Violet 450 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-81063AF350
Alexa Fluor 405
NBP2-81063AF405
Alexa Fluor 488
NBP2-81063AF488
Alexa Fluor 532
NBP2-81063AF532
Alexa Fluor 594
NBP2-81063AF594
Alexa Fluor 647
NBP2-81063AF647
Alexa Fluor 700
NBP2-81063AF700
Alexa Fluor 750
NBP2-81063AF750
Biotin
NBP2-81063B
DyLight 350
NBP2-81063UV
DyLight 405
NBP2-81063V
DyLight 488
NBP2-81063G
DyLight 550
NBP2-81063R
DyLight 594
NBP2-81063DL594
DyLight 650
NBP2-81063C
DyLight 680
NBP2-81063FR
DyLight 755
NBP2-81063IR
FITC
NBP2-81063F
HRP
NBP2-81063H
Janelia Fluor 549
NBP2-81063JF549
Janelia Fluor 646
NBP2-81063JF646
PerCP
NBP2-81063PCP
Unconjugated
NBP2-81063-0.2mg
mFluor Violet 500 SE
NBP2-81063MFV500
mFluor Violet 610 SE
NBP2-81063MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-81063-0.2mg
Azide and BSA Free
NBP2-81063-0.2mg
Azide and BSA Free
NBP2-81063-0.025mg
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Paxillin Antibody (LD4 sAB) [mFluor Violet 450 SE] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Peptide corresponding to human paxillin-LD4 motif (residues 260-278) fused to MBP; peptide sequence: WGGSATRELDELMASLSD.
Specificity
The antibody binds specifically to the LD-4 motif of human Paxillin with a Kd of 6 nM.
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Rabbit
Gene
PXN
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Paxillin Antibody (LD4 sAB) [mFluor Violet 450 SE]

  • FLJ16691
  • Paxillin
  • PXN

Background

Paxillin is a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion) (1). Paxillin plays a significant role in integrin signaling and the tyrosine phosphorylation of paxillin is required for integrin-mediated cytoskeletal reorganization (2). Paxillin is phosphorylated by focal adhesion kinase (FAK) at Tyr118 (3). It has been found that phosphorylation of paxillin at both Tyr118 and Tyr31 is essential for MM1 cancer cell migration (4).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Paxillin Antibody
(LD4 sAB) [mFluor Vio ...
NBP2-81063MFV450
Paxillin Antibody (LD4 sAB) [mFluor Violet 450 SE]
Species: Hu
Applications: WB, ELISA, ICC/IF

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Bioinformatics

Gene Symbol PXN