Paxillin Products

Description

Paxillin is a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion) (1). Paxillin plays a significant role in integrin signaling and the tyrosine phosphorylation of paxillin is required for integrin-mediated cytoskeletal reorganization (2). Paxillin is phosphorylated by focal adhesion kinase (FAK) at Tyr118 (3). It has been found that phosphorylation of paxillin at both Tyr118 and Tyr31 is essential for MM1 cancer cell migration (4).

Bioinformatics

Uniprot	AAH10498 Human AAH10498.1 Human NM_002859 Human NP_002850 Human P49023 Human
Product By Gene ID	5829
Alternate Names	FLJ16691 paxillin

Research Areas for Paxillin

Find related products by research area and learn more about each of the different research areas below.

Cellular Markers
Cytoskeleton Markers
Phospho-Specific
Signal Transduction

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