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PAR2 Antibody (344222) [Allophycocyanin]

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Product Details

Summary
Applications Flow
Clone
344222
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB3949U-100UG
Alexa Fluor 405
FAB3949V-100UG
Alexa Fluor 488
FAB3949G-100UG
Alexa Fluor 532
FAB3949X
Alexa Fluor 594
FAB3949T-100UG
Alexa Fluor 647
FAB3949R-100UG
Alexa Fluor 700
FAB3949N-100UG
Alexa Fluor 750
FAB3949S-100UG
Allophycocyanin/Cy7
FAB3949APCCY7
Biotin
FAB3949B
CoraFluor 1
FAB3949CL1
DyLight 350
FAB3949D
DyLight 405
FAB3949E
DyLight 488
FAB3949K
DyLight 550
FAB3949L
DyLight 594
FAB3949M
DyLight 650
FAB3949W
DyLight 680
FAB3949Y
DyLight 755
FAB3949Z
FITC
FAB3949F
HRP
FAB3949H
Janelia Fluor 525
FAB3949JF525
Janelia Fluor 549
FAB3949I
Janelia Fluor 585
FAB3949JF585
Janelia Fluor 635
FAB3949JF635
Janelia Fluor 646
FAB3949J
Janelia Fluor 669
FAB3949JF669
PE/Atto594
FAB3949PEATT594
PE/Cy5.5
FAB3949PECY55
PE/Cy7
FAB3949PECY7
PerCP
FAB3949C
Phycoerythrin
FAB3949P
Unconjugated
MAB3949
mFluor Violet 450 SE
FAB3949MFV450
mFluor Violet 500 SE
FAB3949MFV500
mFluor Violet 610 SE
FAB3949MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB3949
Carrier Free
FAB3949P
Carrier Free
MAB3949
Carrier Free
MAB3949-SP
Carrier Free
FAB3949V-100UG
Carrier Free
FAB3949U-100UG
Carrier Free
FAB3949T-100UG
Carrier Free
FAB3949S-100UG
Carrier Free
FAB3949R-100UG
Carrier Free
FAB3949N-100UG
Carrier Free
FAB3949G-100UG
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PAR2 Antibody (344222) [Allophycocyanin] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human PAR2
Accession # P55085
Specificity
Detects human PAR2. Stains human PAR2 transfectants but not irrelevant transfectants.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
F2RL1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
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Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

Protease-Activated Receptor 2 (PAR2) is a protease activated 7-transmembrane G-protein-coupled receptor. Human PAR2 contains a cleavage site for trypsin, mast cell tryptase or coagulation factor VIIa or Xa, 11 amino acids (aa) C-terminal to the signal sequence. Cleavage creates a tethered ligand that activates the 361 aa receptor. PAR2 is expressed in kidney, pancreas, stomach, intestine, airway, skin, bladder and brain; activation stimulates release of inflammatory and nociceptive mediators. PAR2 is downregulated by ubiquination, endocytosis and degradation. Mature human PAR2 shows 78% amino acid identity with mouse PAR2 over the extracellular portions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol F2RL1