Species: Hu
Applications: Flow, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Pm
Applications: WB, ELISA, IHC, IP
Host: Rabbit Polyclonal
Species: Hu, Pm
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Rt
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Mu
Applications: AC
Species: Hu
Applications: AP
Description
The Proteinase-activated receptor 2 (PAR2) is a member of the proteinase-activated receptor subfamily. It is activated through proteolytic exposure of an occult tethered ligand by trypsin and trypsin-like proteases. This is in contrast to other members of the subfamily which are activated by the protease thrombin. PAR2 has been implicated in acute inflammatory response, asthma, and pain transmission. PAR2 expression has been documented in the periphery. ESTs have been isolated from adrenal, brain, breast, heart/melanocyte/uterus, kidney, lung, and vessel libraries.
Bioinformatics
Uniprot |
Human Human Human Human |
Product By Gene ID |
2150 |
Alternate Names |
- coagulation factor II (thrombin) receptor-like 1
- Coagulation factor II receptor-like 1
- GPR11protease-activated receptor 2
- G-protein coupled receptor 11
- PAR-2
- PAR2G protein-coupled receptor-11
- proteinase-activated receptor 2
- proteinase-activated receptor-2
- Thrombin receptor-like 1
|
Research Areas for PAR2
Find related products by research area and learn more about each of the different research areas below.
GPCRSignal Transduction