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p70 S6 Kinase/S6K Antibody (215247) [mFluor Violet 450 SE]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC, CyTOF-ready, Flow
Clone
215247
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 450 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC8962U-100UG
Alexa Fluor 405
IC8962V-100UG
Alexa Fluor 488
IC8962G-025
Alexa Fluor 532
FAB8962X
Alexa Fluor 594
IC8962T-100UG
Alexa Fluor 647
IC8962R-100UG
Alexa Fluor 700
IC8962N-100UG
Alexa Fluor 750
IC8962S-100UG
Allophycocyanin
FAB8962A
Biotin
FAB8962B
DyLight 350
FAB8962D
DyLight 405
FAB8962E
DyLight 488
FAB8962K
DyLight 550
FAB8962L
DyLight 594
FAB8962M
DyLight 650
FAB8962W
DyLight 680
FAB8962Y
DyLight 755
FAB8962Z
FITC
FAB8962F
HRP
FAB8962H
Janelia Fluor 549
FAB8962I
Janelia Fluor 646
FAB8962J
PerCP
FAB8962C
Phycoerythrin
IC8962P-025
Unconjugated
MAB8962
mFluor Violet 500 SE
FAB8962MFV500
mFluor Violet 610 SE
FAB8962MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB8962
Carrier Free
MAB8962
Carrier Free
MAB8962-SP
Carrier Free
IC8962P-025
Carrier Free
IC8962G-025
Carrier Free
IC8962V-100UG
Carrier Free
IC8962R-100UG
Carrier Free
IC8962N-100UG
Carrier Free
IC8962U-100UG
Carrier Free
IC8962T-100UG
Carrier Free
IC8962S-100UG
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p70 S6 Kinase/S6K Antibody (215247) [mFluor Violet 450 SE] Summary

Immunogen
E. coli-derived recombinant human p70 S6 Kinase
Accession # M60725
Specificity
Detects human, mouse, and rat p70 S6 Kinase and p85 S6 Kinase. Reactivity with beta isoforms of p70 S6 Kinase is unknown.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
RPS6KB1
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Immunohistochemistry
  • Intracellular Staining by Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for p70 S6 Kinase/S6K Antibody (215247) [mFluor Violet 450 SE]

  • EC 2.7.11
  • EC 2.7.11.1
  • p70 ribosomal S6 kinase alpha
  • p70 S6 kinase alpha
  • p70 S6 Kinase
  • p70 S6 kinase, alpha 1,70 kDa ribosomal protein S6 kinase 1
  • p70 S6 kinase, alpha 2
  • p70 S6KA
  • p70 S6K-alpha
  • p70(S6K)-alpha
  • p70-alpha
  • p70-S6K
  • P70S6K1
  • PS6K
  • ribosomal protein S6 kinase beta-1
  • Ribosomal protein S6 kinase I
  • ribosomal protein S6 kinase, 70kD, polypeptide 1
  • ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • RPS6KB1
  • S6K
  • S6K1
  • S6K1p70-S6K 1
  • S6K-beta-1
  • serine/threonine kinase 14 alpha
  • Serine/threonine-protein kinase 14A
  • STK14A

Background

S6K encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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S6K - a serine/threonine kinase with diverse roles in cell survival and cell cycle progression
S6K is a serine/threonine kinase that is a member of the ribosomal S6 kinase (RSK) family. S6K exists in two main isoforms, S6K1 and S6K2, which can also be alternatively spliced to produce different splice forms. S6K1 has two major splicing produ...  Read full blog post.
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Bioinformatics

Gene Symbol RPS6KB1