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p67phox/NOXA2 Antibody [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Biotin

Order Details

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p67phox/NOXA2 Antibody [Biotin] Summary

Immunogen
Produced in rabbits immunized with purified, recombinant Human p67phox/NOXA2 (Accession#: AAH01606.1; Met1-Val526)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NCF2
Purity
Antigen and protein A Affinity-purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Alternate Names for p67phox/NOXA2 Antibody [Biotin]

  • autosomal 2
  • NADPH oxidase activator 2
  • NCF2
  • NCF-2
  • neutrophil cytosol factor 2
  • neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal2)
  • neutrophil cytosolic factor 2
  • NOXA2
  • NOXA2FLJ93058
  • p67phox
  • p67-phox

Background

NOXA2 encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in two transcript variants that encode the same protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol NCF2