p67phox/NOXA2 Products

Description

NOXA2 encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in two transcript variants that encode the same protein.

Bioinformatics

Uniprot	AAH01606 Human NM_000433 Human NP_001121123 Human P19878 Human
Product By Gene ID	4688
Alternate Names	autosomal 2 NADPH oxidase activator 2 NCF-2 neutrophil cytosol factor 2 neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal2) neutrophil cytosolic factor 2 NOXA2FLJ93058 p67phox P67PHOX p67-phox