Our customer asked us about NBP1-02905, which we lately found it discontinued. While checking its related products, there seems none. Would you please help confirm if there is any replacement available?

Name: p16INK4a/CDKN2A Antibody [Unconjugated]
Brand: Novus Biologicals
SKU: AF5779
Price: 479 USD

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With regards to your question on our CDKN2A antibodies, we do supply a wide range of products, but you haven't specified which application you are referring to. Please go through this link (cyclin-dependent kinase inhibitor 2A) and choose the product that will suit your experiment and the species you are working with. Meanwhile it is important to keep in mind that CDKN2A generates several transcript variants which differ in their first exons.

At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	HuSpecies Glossary
Applications	WB, Simple Western, ICC/IF
Clonality	Polyclonal
Host	Goat
Conjugate	Unconjugated
Concentration	LYOPH

Catalog# & Formulation	Size	Price
Carrier Free AF5779-SP

Immunogen	E. coli-derived recombinant human p16INK4a/CDKN2A Glu2-Asp156 Accession # P42771
Specificity	Detects human p16INK4a/CDKN2A in Western blots.
Source	N/A
Isotype	IgG
Clonality	Polyclonal
Host	Goat
Gene	CDKN2A
Purity Statement	Antigen Affinity-purified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Concentration	LYOPH
Reconstitution Instructions	Reconstitute at 0.2 mg/mL in sterile PBS.

p16INK4a/CDKN2A Antibody [Unconjugated]

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Publications for p16INK4a/CDKN2A Antibody (AF5779)(13)

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Publications using AF5779	Applications	Species
JR Herdy, L Traxler, RK Agarwal, L Karbacher, JCM Schlachetz, L Boehnke, D Zangwill, D Galasko, CK Glass, J Mertens, FH Gage Increased post-mitotic senescence in aged human neurons is a pathological feature of Alzheimer's disease Cell Stem Cell, 2022-12-01;29(12):1637-1652.e6. 2022-12-01 [PMID: 36459967] (Simple Western, Human)	Simple Western	Human
Tom Zimmermann, Michaela Pommer, Viola Kluge, Chafia Chiheb, Susanne Muehlich, Anja-Katrin Bosserhoff Detection of Cellular Senescence in Human Primary Melanocytes and Malignant Melanoma Cells In Vitro Cells 4/28/2022 [PMID: 35563794]
V Farfariell, DV Gordienko, L Mesilmany, Y Touil, E Germain, I Fliniaux, E Desruelles, D Gkika, M Roudbaraki, G Shapovalov, L Noyer, M Lebas, L Allart, N Zienthal-G, O Iamshanova, F Bonardi, M Figeac, W Laine, J Kluza, P Marchetti, B Quesnel, D Metzger, D Bernard, JB Parys, L Lemonnier, N Prevarskay TRPC3 shapes the ER-mitochondria Ca2+ transfer characterizing tumour-promoting senescence Nature Communications, 2022-02-17;13(1):956. 2022-02-17 [PMID: 35177596] (Western Blot, Human)	Western Blot	Human
SL Mathiasen, L Gall-Mas, IS Pateras, SDP Theodorou, MRJ Namini, MB Hansen, OCB Martin, CK Vadivel, K Ntostoglou, D Butter, M Givskov, C Geisler, AN Akbar, VG Gorgoulis, T Frisan, N Ødum, T Krejsgaard Bacterial genotoxins induce Tï¿½cell senescence Cell Reports, 2021-06-08;35(10):109220. 2021-06-08 [PMID: 34107253] (Western Blot, Human)	Western Blot	Human
Rachael E. Schwartz, Maxim N. Shokhirev, Leonardo R. Andrade, J. Silvio Gutkind, Ramiro Iglesias-Bartolome, Gerald S. Shadel Insights into epithelial cell senescence from transcriptome and secretome analysis of human oral keratinocytes Aging (Albany NY) 2/28/2021 [PMID: 33601339]
P Sachamitr, JC Ho, FE Ciamponi, W Ba-Alawi, FJ Coutinho, P Guilhamon, MM Kushida, FMG Cavalli, L Lee, N Rastegar, V Vu, M Sánchez-Os, J Coulombe-H, E Kanshin, H Whetstone, M Durand, P Thibault, K Hart, M Mangos, J Veyhl, W Chen, N Tran, BC Duong, AM Aman, X Che, X Lan, O Whitley, O Zaslaver, D Barsyte-Lo, LM Richards, I Restall, A Caudy, HL Röst, ZQ Bonday, M Bernstein, S Das, MD Cusimano, J Spears, GD Bader, TJ Pugh, M Tyers, M Lupien, B Haibe-Kain, H Artee Luch, S Weiss, KB Massirer, P Prinos, CH Arrowsmith, PB Dirks PRMT5 inhibition disrupts splicing and stemness in glioblastoma Nature Communications, 2021-02-12;12(1):979. 2021-02-12 [PMID: 33579912] (Western Blot, Human)	Western Blot	Human
Ruizhu Lin, Lea Rahtu-Korpela, Johanna Magga, Johanna Ulvila, Julia Swan, Anna Kemppi et al. miR-1468-3p Promotes Aging-Related Cardiac Fibrosis Molecular Therapy - Nucleic Acids 6/5/2020 [PMID: 32348937]
P Vijayaraj, A Minasyan, A Durra, S Karumbayar, M Mehrabi, CJ Aros, SD Ahadome, DW Shia, K Chung, JM Sandlin, KF Darmawan, KV Bhatt, CC Manze, MK Paul, DC Wilkinson, W Yan, AT Clark, TM Rickabaugh, WD Wallace, TG Graeber, R Damoiseaux, BN Gomperts Modeling Progressive Fibrosis with Pluripotent Stem Cells Identifies an Anti-fibrotic Small Molecule Cell Rep, 2019-12-10;29(11):3488-3505.e9. 2019-12-10 [PMID: 31825831] (ICC, Western Blot, Human)	ICC, Western Blot	Human
Jianjun Wang, Yongliang Yao, Qinghui Zhang, Shasha Li, Lijun Tang Inflammatory responses induced by Helicobacter pylori on the carcinogenesis of gastric epithelial GES‑1 cells International Journal of Oncology 4/9/2019 [PMID: 31081048]
SY Choi, BH Bin, W Kim, E Lee, TR Lee, EG Cho Exposure of human melanocytes to UVB twice and subsequent incubation leads to cellular senescence and senescence-associated pigmentation through the prolonged p53 expression J. Dermatol. Sci., 2018-03-02;0(0):. 2018-03-02 [PMID: 29525471] (Western Blot, Human)	Western Blot	Human
IM Schaefer, Y Wang, CW Liang, N Bahri, A Quattrone, L Doyle, A Mariño-Enr, A Lauria, M Zhu, M Debiec-Ryc, S Grunewald, JF Hechtman, A Dufresne, CR Antonescu, C Beadling, ET Sicinska, M van de Rij, GD Demetri, M Ladanyi, CL Corless, MC Heinrich, CP Raut, S Bauer, JA Fletcher MAX inactivation is an early event in GIST development that regulates p16 and cell proliferation Nat Commun, 2017-03-08;8(0):14674. 2017-03-08 [PMID: 28270683] (Western Blot, Human)	Western Blot	Human
Taewon Jin Adiponectin corrects premature cellular senescence and normalizes antimicrobial peptide levels in senescent keratinocytes Biochem Biophys Res Commun, 2016-06-25;0(0):. 2016-06-25 [PMID: 27349869] (Western Blot, Human)	Western Blot	Human
Hirshoren N, Bulvik R, Neuman T, Rubinstein A, Meirovitz A, Elkin M Induction of heparanase by HPV E6 oncogene in head and neck squamous cell carcinoma. J Cell Mol Med, 2013-11-28;18(1):181-6. 2013-11-28 [PMID: 24286246] (IHC, Human)	IHC	Human
Show All 13 Publications. Collapse Publications.

Gene Symbol	CDKN2A
Uniprot	P42771()