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OTOA Antibody

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Immunohistochemistry-Paraffin: OTOA Antibody [NBP1-84363] - Staining of human spleen shows strong cytoplasmic positivity in cells of red pulp.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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OTOA Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: RCMEEDTFIRTVELLGAVQGFSRPQLMTLKEKAIQVWDMPSYWREHHIVSLGRIALALNESELEQLDLSSIDTVASLSWQTEWTP
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
OTOA
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
OTOA Protein (NBP1-84363PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (87%), Rat (88%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for OTOA Antibody

  • cancer/testis antigen 108
  • CT108
  • deafness, autosomal recessive 22
  • DFNB22
  • FLJ32773
  • MGC157747
  • MGC39813
  • OTOA
  • otoancorin

Background

The protein encoded by the OTOA gene is specifically expressed in the inner ear, and is located at the interface betweenthe apical surface of the inner ear sensory epithelia and their overlying acellular gels. It is prposed that thisprotein is involved in the attachment of the inner ear acellular gels to the apical surface of the underlyingnonsensory cells. Mutations in this gene are associated with autosomal recessive deafness type 22 (DFNB22).Alternatively spliced transcript variants encoding different isoforms have been found for this gene. (provided byRefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol OTOA