Mesothelin Antibody (420404) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Mesothelin is a 40 kDa glycosylphosphatidylinositol-anchored glycoprotein that is expressed on mesothelial cells in the pleura, pericardium and peritoneum and overexpressed in mesotheliomas and ovarian or pancreatic adenocarcinoma. Mesothelin is a product of the CAK-1 gene, which also encodes megakaryocyte-potentiating factor (MPF). Mature human mesothelin shares 60% amino acid identity with either mouse or rat mesothelin. Two variant forms exist; variant 1 has an eight amino acid (1 kDa) insertion and is rarely expressed, while variant 2 is a truncated form secreted in the majority of ovarian cancers but rarely found in normal individuals.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Images	Ratings	Applications	Species	Date	Details
	4 reviewed by: Verified Customer	ICC	Rat	02/19/2015	View Summary Application Immunocytochemistry Sample Tested See PMID 22705407 Species Rat

Array MAB32651

• Mesothelin Antibodies
• Mesothelin Lysate
• Mesothelin Protein
• Mesothelin Proteins and Enzymes
• Mesothelin ELISAs