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OSMR beta Antibody (118125) [Phycoerythrin]

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D3 mouse embryonic stem cell line was stained with Rat Anti-Mouse OSM R beta PE-conjugated Monoclonal Antibody (Catalog # FAB662P, filled histogram) or isotype control antibody (IC006P, open histogram). View our protocol for Staining Membrane-associated Proteins.
D3 mouse embryonic stem cell line was stained with Rat Anti-Mouse OSM R beta PE-conjugated Monoclonal Antibody (Catalog # FAB662P, filled histogram) or isotype control antibody (IC006P, open histogram). View our ...read more
3T3-L1 cells were stained with Rat Anti-Mouse OSMR beta PE‑conjugated Monoclonal Antibody (Catalog # FAB662P, filled histogram) or isotype control antibody (Catalog # IC006P, open histogram). View our ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
118125
Clonality
Monoclonal
Host
Rat
Conjugate
Phycoerythrin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 532
FAB662X
Allophycocyanin
FAB662A
Biotin
BAM662
CoraFluor 1
FAB662CL1
DyLight 350
FAB662D
DyLight 405
FAB662E
DyLight 488
FAB662K
DyLight 550
FAB662L
DyLight 594
FAB662M
DyLight 650
FAB662W
DyLight 680
FAB662Y
DyLight 755
FAB662Z
FITC
FAB662F
HRP
FAB662H
Janelia Fluor 525
FAB662JF525
Janelia Fluor 549
FAB662I
Janelia Fluor 646
FAB662J
Janelia Fluor 669
FAB662JF669
PerCP
FAB662C
Unconjugated
MAB662
mFluor Violet 450 SE
FAB662MFV450
mFluor Violet 500 SE
FAB662MFV500
mFluor Violet 610 SE
FAB662MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB662
Carrier Free
MAB662
Carrier Free
MAB662-SP
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OSMR beta Antibody (118125) [Phycoerythrin] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse OSM R beta
Glu24-Leu738
Accession # O70458
Specificity
Detects mouse OSM R beta in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) CLC, rhCNTF, rhOSM, recombinant mouse (rm) CT-1, rmIL-6, rmIL-11, or rmLIF is observed.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
Osmr
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB662P in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for OSMR beta Antibody (118125) [Phycoerythrin]

  • IL-31 receptor subunit beta
  • IL-31R subunit beta
  • IL-31RB
  • IL-31R-beta
  • Interleukin-31 receptor subunit beta
  • MGC150627
  • MGC75127
  • oncostatin M receptor
  • oncostatin-M specific receptor beta subunit
  • oncostatin-M-specific receptor subunit beta
  • OSM R beta
  • OSMR beta
  • OSMR
  • OSMRB
  • OSMRBMGC150626
  • PLCA1

Background

Oncostatin M (OSM) is a member of the IL-6 family of cytokines that share the gp130 as a common signal transducing receptor subunit. Human OSM signals through two types of human OSM receptor complexes: the type I complex comprising the leukemia inhibitory factor receptor beta (LIF R beta ) and gp130, the type II complex made up of OSM receptor beta (OSM R beta ) and gp130. In contrast, mouse OSM signals only through the mouse OSM R beta and gp130 complex. Mouse OSM R beta cDNA encodes a 971 amino acid (aa) type I transmembrane protein which contains a 23 aa signal peptide, an extracellular domain of 714 aa, a transmembrane domain of 20 aa and a 214 aa cytoplasmic domain. Mouse OSM R beta alone binds mOSM with low-affinity but forms a high-affinity binding complex in the presence of gp130. Mouse OSM R beta is 55% identical at the amino acid sequence level to human OSM R beta .

  1. Lindberg, R.A. et al. (1998) Mol. Cell. Biol. 18:3357.
  2. Tanaka, M. et al. (1999) Blood 93:804.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for OSMR beta Antibody (FAB662P)(2)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 2 applications: Flow Cytometry, IHC.


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Bioinformatics

Gene Symbol Osmr
Uniprot