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OFD1 Antibody

Images

 
Immunohistochemistry-Paraffin: OFD1 Antibody [NBP1-89355] - Staining of human endometrium shows moderate cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: OFD1 Antibody [NBP1-89355] - Staining of human testis shows strong cytoplasmic positivity in seminiferous ducts.
Immunohistochemistry-Paraffin: OFD1 Antibody [NBP1-89355] - Staining of human prostate shows strong cytoplasmic positivity in smooth muscle cells.
Immunohistochemistry-Paraffin: OFD1 Antibody [NBP1-89355] - Staining of human stomach shows moderate cytoplasmic positivity in glandular cells.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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OFD1 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: LLKEEKLELLAQNKLLKQQLEESRNENLRLLNRLAQPAPELAVFQKELRKAEKAIVVEHEEFESCRQALHKQLQDEIEHSAQLKAQILGYKA
Localization
Cytoskeleton (microtubules)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
OFD1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence Reported in scientific literature (PMID:34078910)
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
  • Western Blot Reported in scientific literature (PMID: 25180832)
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
OFD1 Protein (NBP1-89355PEP)
Publications
Read Publications using
NBP1-89355 in the following applications:

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 25180832).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for OFD1 Antibody

  • JBTS10
  • MGC117039
  • oral-facial-digital syndrome 1
  • SGBS2

Background

The OFD1 gene is located on the X chromosome and encodes a centrosomal protein. A knockout mouse model has been used to study the effect of mutations in this gene. The mouse gene is also located on the X chromosome, however, unlike the human gene it is not su

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for OFD1 Antibody (NBP1-89355)(9)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 3 applications: ICC/IF, IF/IHC, WB.


Filter By Application
ICC/IF
(3)
IF/IHC
(1)
WB
(2)
All Applications
Filter By Species
Human
(4)
Mouse
(2)
All Species
Showing Publications 1 - 9 of 9.
Publications using NBP1-89355 Applications Species
Chao Y, Huang B, Peng I et al. ATM- and ATR-Induced Primary Ciliogenesis Promotes Cisplatin Resistance in Pancreatic Ductal Adenocarcinoma Research Square 2021-12-02 [PMID: 36251015]
Yamamoto Y, Chino H, Tsukamoto S et al. NEK9 regulates primary cilia formation by acting as a selective autophagy adaptor for MYH9/myosin IIA Nature communications 2021-06-02 [PMID: 34078910] (IF/IHC, WB, ICC/IF, Mouse, Human) IF/IHC, WB, ICC/IF Mouse, Human
Wang WJ, Tay HG, Soni R et al. CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base. Nat Cell Biol 2013-06-01 [PMID: 23644468]
Pajkos M, Szaniszló T, Fülöp M, Dosztányi Z Entering new circles: Expansion of the LC8/DYNLL1 interactome in the ciliary-centrosomal network through system-driven motif evolution bioRxiv 2023-09-17 (ICC/IF, Human) ICC/IF Human
Chen TY, Huang BM, Tang TK, et al. Genotoxic stress-activated DNA-PK-p53 cascade and autophagy cooperatively induce ciliogenesis to maintain the DNA damage response Cell death and differentiation 2021-01-18 [PMID: 33462409]
Chen TY, Lin TC, Kuo PL et al. Septin 7 is a centrosomal protein that ensures S phase entry and microtubule nucleation by maintaining the abundance of p150glued J. Cell. Physiol. 2020-09-01 [PMID: 32869310]
Zhang C, Li C et al. Distinct Roles of TRAPPC8 and TRAPPC12 in Ciliogenesis via Their Interactions With OFD1. Front Cell Dev Biol 2020-08-04 [PMID: 32258032] (ICC/IF, Human) ICC/IF Human
Takahashi K, Nagai T, Chiba S et al. Glucose deprivation induces primary cilium formation through mTORC1 inactivation J. Cell. Sci. 2017-11-27 [PMID: 29180513] (Human) Human
Jerman S, Ward HH, Lee R et al. OFD1 and Flotillins Are Integral Components of a Ciliary Signaling Protein Complex Organized by Polycystins in Renal Epithelia and Odontoblasts. PLoS ONE. 2014-09-03 [PMID: 25180832] (WB, Mouse) WB Mouse

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for OFD1 Antibody (NBP1-89355) (0)

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Secondary Antibodies

 

Isotype Controls

Additional OFD1 Products

Array NBP1-89355

Research Areas for OFD1 Antibody (NBP1-89355)

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Blogs on OFD1

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Bioinformatics

Gene Symbol OFD1
Entrez
Uniprot