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OAS2 Antibody (OTI6E6) [DyLight 350]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
OTI6E6
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 350

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OAS2 Antibody (OTI6E6) [DyLight 350] Summary

Immunogen
Recombinant protein fragment corresponding to amino acids 60-335 of human OAS2 (NP_002526) produced in E.coli.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
OAS2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for OAS2 Antibody (OTI6E6) [DyLight 350]

  • (2-5')oligo(A) synthase 2
  • (2'-5')oligo(A) synthetase 2
  • (2-5')oligo(A) synthetase 2
  • 2'5' oligoadenylate synthetase 2
  • 2-5A synthase 2
  • 2-5A synthetase 2
  • 2'-5'-oligoadenylate synthase 2
  • 2'-5'-oligoadenylate synthetase 2 (69-71 kD)
  • 2'-5'-oligoadenylate synthetase 2, 69/71kDa
  • EC 2.7.7
  • EC 2.7.7.-
  • MGC78578
  • OAS2
  • p69 OAS / p71 OAS
  • p69OAS / p71OAS

Background

OAS2 encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol OAS2