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Notch-4 Antibody (SR3217)

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Western Blot: Notch-4 Antibody (SR3217) [NBP3-27755] - Western blot analysis of Mouse lung lysate.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, Flow
Clone
SR3217
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Notch-4 Antibody (SR3217) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthesized peptide derived from human Notch-4 (Uniprot #: Q99466)
Specificity
Detects endogenous levels of total Notch-4
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
NOTCH4
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:50
  • Western Blot 1:100-1:500
Theoretical MW
230 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4), 150mM NaCl, 50% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Notch-4 Antibody (SR3217)

  • INT3
  • neurogenic locus notch homolog protein 4
  • notch 4
  • Notch homolog 4
  • NOTCH3
  • Notch4
  • Notch-4

Background

NOTCH4 encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. This gene may be associated with susceptibility to schizophrenia in a small portion of cases (entrez gene).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol NOTCH4