Species: Hu
Applications: WB, ICC/IF
Host: Goat Polyclonal
Species: Hu
Applications: WB, ICC/IF
Host: Rat Monoclonal
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: Bioactivity
Description
NOTCH4 encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. This gene may be associated with susceptibility to schizophrenia in a small portion of cases (entrez gene).
Bioinformatics
| Uniprot |
Human
|
| Product By Gene ID |
4855 |
| Alternate Names |
- neurogenic locus notch homolog protein 4
- notch 4
- Notch homolog 4
- NOTCH3
|
Research Areas for Notch-4
Find related products by research area and learn more about each of the different research areas below.
Angiogenesis
![Immunocytochemistry Notch-4 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/antibody/af3847_human-notch-4-intracellular-domain-affinity-purified-pab-immunocytochemistry-3092021102949.jpg)
![Immunocytochemistry Notch-4 Antibody (411913) [Unconjugated]](http://images.novusbio.com/fullsize2/Notch4_MAB3847_Immunocytochemistry__Immunofluorescence_20088.jpg)
![Binding Activity Notch-4 [Unconjugated]](http://images.novusbio.com/fullsize2/Notch4_9909NT_2011.jpg)
![SDS-PAGE Notch-4 [Unconjugated]](http://images.novusbio.com/fullsize2/Notch4_9909NT_1951.jpg)