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NCAM-1/CD56 Antibody (NCAM1/9121R) [DyLight 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
NCAM1/9121R
Clonality
Monoclonal
Host
Rabbit
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-23979AF350
Alexa Fluor 405
NBP3-23979AF405
Alexa Fluor 488
NBP3-23979AF488
Alexa Fluor 532
NBP3-23979AF532
Alexa Fluor 594
NBP3-23979AF594
Alexa Fluor 647
NBP3-23979AF647
Alexa Fluor 700
NBP3-23979AF700
Alexa Fluor 750
NBP3-23979AF750
Allophycocyanin
NBP3-23979APC
Biotin
NBP3-23979B
DyLight 350
NBP3-23979UV
DyLight 405
NBP3-23979V
DyLight 550
NBP3-23979R
DyLight 594
NBP3-23979DL594
DyLight 650
NBP3-23979C
DyLight 680
NBP3-23979FR
DyLight 755
NBP3-23979IR
FITC
NBP3-23979F
HRP
NBP3-23979H
Janelia Fluor 549
NBP3-23979JF549
Janelia Fluor 646
NBP3-23979JF646
PE
NBP3-23979PE
PerCP
NBP3-23979PCP
Unconjugated
NBP3-23979
mFluor Violet 450 SE
NBP3-23979MFV450
mFluor Violet 500 SE
NBP3-23979MFV500
mFluor Violet 610 SE
NBP3-23979MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP3-23979
Azide and BSA Free
NBP3-23979
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NCAM-1/CD56 Antibody (NCAM1/9121R) [DyLight 488] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Recombinant fragment (around aa200-400) of human NCAM-1/CD56 protein (exact sequence is proprietary)
Localization
Cell surface. Cytoplasm.
Marker
Neuronal Cell Marker
Specificity
This monoclonal antibody reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas).
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Rabbit
Gene
NCAM1
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for NCAM-1/CD56 Antibody (NCAM1/9121R) [DyLight 488]

  • CD56 / NCAM-1
  • CD56 antigen
  • CD56
  • MSK39
  • NCAM1
  • N-CAM-1
  • NCAM-1
  • NCAMantigen recognized by monoclonal 5.1H11
  • neural cell adhesion molecule 1
  • neural cell adhesion molecule, NCAM

Background

NCAM, as a member of the immunoglobulin superfamily of adhesion molecules is characterized by several immunoglobulin (Ig) like domains. The extracellular part of NCAM consists of five of these Ig domains and two fibronectin type III homology regions. NCAM is encoded by a single copy gene composed of 26 exons. However, at least 20-30 distinct isoforms can be generated by alternative splicing and by posttranslational modifications, such as sialylation. During sialylation, polysialic acid (PSA) carbohydrates are attached to the extracellular part of NCAM. Through its extracellular region, NCAM mediates homophilic interactions. In addition, NCAM can also undergo heterophilic interactions by binding extracellular matrix components, such as laminin, or other cell adhesion molecules, such as integrins. NCAM is expressed on most neuroectodermal derived cell lines, tissues and neoplasm such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NCAM-1/CD56
Antibody (NCAM1/9121R ...
NBP3-23979G
NCAM-1/CD56 Antibody (NCAM1/9121R) [DyLight 488]
Species: Hu
Applications: IHC

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Bioinformatics

Gene Symbol NCAM1