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Nav1.7 Antibody (N68/6) [Alexa Fluor® 488]

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Product Details

Summary
Reactivity Hu, Mu, Rt, HaSpecies Glossary
Applications ICC/IF, IHC, IP
Clone
N68/6
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 488

Nav1.7 Antibody (N68/6) [Alexa Fluor® 488] Summary

Immunogen
Fusion protein amino acids 1751-1946 (C-terminus) of human Nav1.7
Localization
Membrane , Synapse
Specificity
Detects approx 230kDa. No cross-reactivity against other Nav channels.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SCN9A
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Nav1.7 Antibody (N68/6) [Alexa Fluor® 488]

  • ETHA
  • FEB3B
  • hNE-Na
  • Nav1.7
  • NENA
  • NE-NA
  • NENAVoltage-gated sodium channel subunit alpha Nav1.7
  • Neuroendocrine sodium channel
  • Peripheral sodium channel 1
  • PN1
  • PN1hNE-Na
  • SCN9A
  • sodium channel protein type 9 subunit alpha
  • Sodium channel protein type IX subunit alpha
  • sodium channel, voltage-gated, type IX, alpha subunit
  • voltage-gated sodium channel alpha subunit Nav1.7
  • voltage-gated, type IX, alpha polypeptide

Background

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-sensitive Na(+) channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain (from SwissProt).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional Nav1.7 Products

Array NBP2-12904AF488

Research Areas for Nav1.7 Antibody (NBP2-12904AF488)

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Bioinformatics

Gene Symbol SCN9A