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Myotilin Antibody

Images

 
Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361] - Staining of human testis.
Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361] - Staining of human skeletal muscle shows high expression.
Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361] - Staining of human skin shows low expression as expected.
Orthogonal Strategies: Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361] - Staining in human skeletal muscle and skin tissues using anti-MYOT antibody. Corresponding MYOT RNA-seq data are presented ...read more
Independent Antibodies: Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361] - Staining of human cerebral cortex, lymph node, skeletal muscle and testis using Anti-MYOT antibody NBP2-38361 (A) shows ...read more
Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361] - Staining of human lymph node.
Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361] - Staining of human cerebral cortex.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Myotilin Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: ACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG
Predicted Species
Mouse (93%), Rat (95%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MYOT
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Myotilin Protein (NBP2-38361PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Myotilin Antibody

  • 57 kDa cytoskeletal protein
  • LGMD1A
  • limb-girdle muscular dystrophy 1A (autosomal dominant)
  • Myofibrillar titin-like Ig domains protein
  • myotilin
  • titin immunoglobulin domain protein (myotilin)
  • Titin immunoglobulin domain protein
  • TTIDLGMD1

Background

Striated muscle sarcomeres are highly organized structures composed of actin (thin) and myosin (thick) filaments that slide past each other during contraction. The integrity of sarcomeres is controlled by a set of structural proteins, among which are titin (TTN; MIM 188840), a giant molecule that contains several immunoglobulin (Ig)-like domains and associates with thin and thick filaments, and alpha-actinin (ACTN1; MIM 102575), an actin cross-linking protein. Mutations in several sarcomeric and sarcolemmal proteins have been shown to result in muscular dystrophy and cardiomyopathy.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol MYOT
Uniprot