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MSP/MST1 Antibody (68801) [Biotin] - Beta Chain

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA(Det)
Clone
68801
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Unconjugated
MAB735
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB735
Carrier Free
MAB735
Carrier Free
MAB735-SP
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MSP/MST1 Antibody (68801) [Biotin] - Beta Chain Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human MSP beta chain
Accession # P26927
Specificity
Detects recombinant human (rh)MSP in direct ELISAs and Western blots. When used in combination with the monoclonal capture antibody (Catalog # MAB352) in sandwich ELISAs, less than 0.001% cross-reactivity was observed with rhHGF, rhIL-9 R, rhMSP alpha or rmMSP R.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
MST1
Purity Statement
Protein A or G purified from ascites
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Applications/Dilutions

Dilutions
  • ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
  • ELISA Detection (Matched Antibody Pair) 0.5-2.0 ug/mL
  • ELISA Standard (Matched Pair)
  • Western Blot 1 ug/mL
Application Notes
ELISA Capture: Human MSP alpha Chain Antibody (Catalog # MAB352)
ELISA Detection: Human MSP/MST1 beta Chain Biotinylated Antibody (Catalog # BAM3521)
Standard: Recombinant Human MSP/MST1 (Catalog # 352-MS)
Readout System

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MSP/MST1 Antibody (68801) [Biotin] - Beta Chain

  • D3F15S2
  • EC 3.4.21
  • hepatocyte growth factor-like protein homolog
  • HGFL
  • HGFLhepatocyte growth factor-like protein
  • macrophage stimulating 1 (hepatocyte growth factor-like)
  • Macrophage stimulatory protein
  • Macrophage-stimulating protein
  • MSP
  • MSPDNF15S2
  • MST1
  • NF15S2
  • SF2

Background

MSP, also known as hepatocyte growth factor-like protein (HGFl), and scatter factor-2 (SF2), is a member of the HGF family of growth factors. It is secreted as a single chain inactive precursor which is proteolytically activated to yield a biologically active disulfide-linked heterodimer of the alpha and beta chains. MSP induces keratinocyte proliferation, bone resorption, and cell migration and shape change in resident macrophages. Heterodimeric MSP binds to and activates the cell surface receptor tyrosine kinase, RON/STK, which is expressed on mature macrophages, keratinocytes, and vascular endothelium of wounded skin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MST1
Uniprot