Name: Mouse VEGFR1/Flt-1 Quantikine ELISA Kit
Brand: Novus Biologicals
SKU: MVR100
Price: 635 USD

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	MuSpecies Glossary
Applications	ELISA
Conjugate	HRP

Background	The Quantikine Mouse soluble VEGF R1 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure mouse sVEGF R1 in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant mouse VEGF R1 and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant factor. Results obtained using natural mouse sVEGF R...1 showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring mouse sVEGF R1. Show More
Specificity	Natural and recombinant mouse sVEGF R1
Source	N/A
Assay Type	Solid Phase Sandwich ELISA
Inter-Assay	See PDF Datasheet for details
Intra-Assay	See PDF Datasheet for details
Spike Recovery	See PDF Datasheet for details
Sample Volume	See PDF Datasheet for details
Gene	Flt1

Publications using MVR100	Applications	Species
Yang, Z;Jia, X;Deng, Q;Luo, M;Hou, Y;Yue, J;Mei, J;Shan, N;Wu, Z; Human umbilical cord mesenchymal stem cell-derived extracellular vesicles loaded with TFCP2 activate Wnt/?-catenin signaling to alleviate preeclampsia International immunopharmacology 2023-02-01 [PMID: 37724958] (Mouse)		Mouse
X Liu, Z Li, J Sun, Z Zhang, W Li Interaction between PD-L1 and soluble VEGFR1 in glioblastoma-educated macrophages BMC Cancer, 2023-03-20;23(1):259. 2023-03-20 [PMID: 36941554] (Human)		Human
SL Lu, H Omori, Y Zhou, YS Lin, CC Liu, JJ Wu, T Noda VEGF-Mediated Augmentation of Autophagic and Lysosomal Activity in Endothelial Cells Defends against Intracellular Streptococcus pyogenes MBio, 2022-07-05;0(0):e0123322. 2022-07-05 [PMID: 35862783] (Mouse)		Mouse
M Jones-Muha, Q Shao, L Cain-Shiel, JP Shaffery, JP Warrington Acid Sensing Ion Channel 2a Is Reduced in the Reduced Uterine Perfusion Pressure Mouse Model and Increases Seizure Susceptibility in Pregnant Mice Cells, 2021-05-08;10(5):. 2021-05-08 [PMID: 34066660] (Mouse)		Mouse
YY Shin, SM An, JS Jeong, SY Yang, GS Lee, EJ Hong, EB Jeung, SC Kim, BS An Comparison of steroid hormones inï¿½threeï¿½different preeclamptic models Molecular Medicine Reports, 2021-02-04;23(4):. 2021-02-04 [PMID: 33537808] (Human, Rat)		Human, Rat
JG Parchem, K Kanasaki, SB Lee, M Kanasaki, JL Yang, Y Xu, KM Earl, RA Keuls, VH Gattone, R Kalluri STOX1 deficiency is associated with renin-mediated gestational hypertension and placental defects JCI Insight, 2021-01-25;0(0):. 2021-01-25 [PMID: 33301424] (Mouse)		Mouse
DJ Dijkstra, RN Verkaik-Sc, S Eskandar, A Limonciel, V Stojanovsk, SA Scherjon, T Plösch Mid-gestation low-dose LPS administration results in female-specific excessive weight gain upon a western style diet in mouse offspring Sci Rep, 2020-11-12;10(1):19618. 2020-11-12 [PMID: 33184349] (Mouse)		Mouse
L Erlandsson, A Ducat, J Castille, I Zia, G Kalapothar, E Hedström, JL Vilotte, D Vaiman, SR Hansson Alpha-1 microglobulin as a potential therapeutic candidate for treatment of hypertension and oxidative stress in the STOX1 preeclampsia mouse model Sci Rep, 2019-06-12;9(1):8561. 2019-06-12 [PMID: 31189914] (Mouse)		Mouse
MW Cunningham, J Castillo, T Ibrahim, DC Cornelius, N Campbell, L Amaral, VR Vaka, N Usry, JM Williams, B LaMarca AT1-AA (Angiotensin II Type 1 Receptor Agonistic Autoantibody) Blockade Prevents Preeclamptic Symptoms in Placental Ischemic Rats Hypertension, 2018-03-19;0(0):. 2018-03-19 [PMID: 29555668] (Rat)		Rat
KD Beharry, CL Cai, T Ahmad, S Guzel, GB Valencia, JV Aranda Impact of Chronic Neonatal Intermittent Hypoxia on Severity of Retinal Damage in a Rat Model of Oxygen-Induced Retinopathy J Nat Sci, 2018-01-01;4(3):. 2018-01-01 [PMID: 29552637] (Rat)		Rat
D Reijnders, CC Liu, X Xu, A Zhao, K Olson, SD Butler, NC Douglas, JL Sones Celecoxib restores angiogenic factor expression at the maternal-fetal interface in the BPH/5 mouse model of preeclampsia Physiol. Genomics, 2018-03-09;0(0):. 2018-03-09 [PMID: 29521599] (ELISA Detection, Mouse)	ELISA Detection	Mouse
SM Blois, N Freitag, I Tirado-Gon, SB Cheng, MM Heimesaat, S Bereswill, M Rose, ML Conrad, G Barrientos, S Sharma NK cell-derived IL-10 is critical for DC-NK cell dialogue at the maternal-fetal interface Sci Rep, 2017-05-19;7(1):2189. 2017-05-19 [PMID: 28526846] (Mouse)		Mouse
P Himmels, I Paredes, H Adler, A Karakatsan, R Luck, HH Marti, O Ermakova, E Rempel, ET Stoeckli, C Ruiz de Al Motor neurons control blood vessel patterning in the developing spinal cord Nat Commun, 2017-03-06;8(0):14583. 2017-03-06 [PMID: 28262664] (Mouse)		Mouse
Luise Erpenbeck PAD4 Deficiency Decreases Inflammation and Susceptibility to Pregnancy Loss in a Mouse Model Biol. Reprod, 2016-11-09;95(6):132. 2016-11-09 [PMID: 28007693] (Mouse)		Mouse
J Morgan Denney Renin-Angiotensin System Transgenic Mouse Model Recapitulates Pathophysiology Similar to Human Preeclampsia with Renal Injury that may be Mediated through VEGF Am. J. Physiol. Renal Physiol, 2016-12-07;0(0):ajprenal.0010. 2016-12-07 [PMID: 27927648] (Mouse)		Mouse
Reduced Uterine Perfusion Pressure (RUPP) Model of Preeclampsia in Mice PLoS ONE, 2016-05-17;11(5):e0155426. 2016-05-17 [PMID: 27187738] (Mouse)		Mouse
Venditti , Carolina, Casselman , Richard, Young , Iain, Karumanchi , S Ananth, Smith , Graeme N Carbon monoxide prevents hypertension and proteinuria in an adenovirus sFlt-1 preeclampsia-like mouse model. PLoS ONE, 2014-09-09;9(9):e106502. 2014-09-09 [PMID: 25202912] (Mouse)		Mouse
Ayala de la Pena F, Kanasaki K, Kanasaki M, Vong S, Rovira C, Kalluri R Specific activation of K-RasG12D allele in the bladder urothelium results in lung alveolar and vascular defects. PLoS ONE, 2014-04-23;9(4):e95888. 2014-04-23 [PMID: 24760005] (Mouse)		Mouse
Luo Y, Kumar P, Chen C, Latham J, Wang L, Tudela C, Alexander J, Shelton J, McKown L, Mendelson C Estrogen-related receptor gamma serves a role in blood pressure homeostasis during pregnancy. Mol Endocrinol, 2014-04-11;28(6):965-75. 2014-04-11 [PMID: 24725083] (Mouse)		Mouse
Craici , Iasmina, Wagner , Steven J, Weissgerber , Tracey L, Grande , Joseph P, Garovic , Vesna D Advances in the pathophysiology of pre-eclampsia and related podocyte injury. Kidney Int, 2014-02-26;86(2):275-85. 2014-02-26 [PMID: 24573315] (Rat)		Rat
Justiniano S, Elavazhagan S, Fatehchand K, Shah P, Mehta P, Roda J, Mo X, Cheney C, Hertlein E, Eubank T, Marsh C, Muthusamy N, Butchar J, Byrd J, Tridandapani S Fcgamma receptor-induced soluble vascular endothelial growth factor receptor-1 (VEGFR-1) production inhibits angiogenesis and enhances efficacy of anti-tumor antibodies. J Biol Chem, 2013-07-31;288(37):26800-9. 2013-07-31 [PMID: 23902770] (Mouse)		Mouse
Suryawanshi A, Mulik S, Sharma S Ocular neovascularization caused by herpes simplex virus type 1 infection results from breakdown of binding between vascular endothelial growth factor A and its soluble receptor. J. Immunol., 2011-02-16;186(6):3653-65. 2011-02-16 [PMID: 21325621] (Mouse)		Mouse
Kalkunte S, Boij R, Norris W Sera from preeclampsia patients elicit symptoms of human disease in mice and provide a basis for an in vitro predictive assay. Am. J. Pathol., 2010-10-01;177(5):2387-98. 2010-10-01 [PMID: 20889559] (Mouse)		Mouse
Tam Tam KB, Lamarca B, Arany M, Cockrell K, Fournier L, Murphy S, Martin JN, Granger JP Role of reactive oxygen species during hypertension in response to chronic antiangiogenic factor (sFlt-1) excess in pregnant rats. Am. J. Hypertens., 2010-08-19;24(1):110-3. 2010-08-19 [PMID: 20725052] (Rat)		Rat
Mazzone M, Dettori D, Leite de Oliveira R, Loges S, Schmidt T, Jonckx B, Tian YM, Lanahan AA, Pollard P, Ruiz de Almodovar C, De Smet F, Vinckier S, Aragones J, Debackere K, Luttun A, Wyns S, Jordan B, Pisacane A, Gallez B, Lampugnani MG, Dejana E, Simons M, Ratcliffe P, Maxwell P, Carmeliet P Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization. Cell, 2009-02-12;136(5):839-51. 2009-02-12 [PMID: 19217150] (Mouse)		Mouse
Satofuka S, Ichihara A, Nagai N, Noda K, Ozawa Y, Fukamizu A, Tsubota K, Itoh H, Oike Y, Ishida S (Pro)renin receptor promotes choroidal neovascularization by activating its signal transduction and tissue renin-angiotensin system. Am. J. Pathol., 2008-10-30;173(6):1911-8. 2008-10-30 [PMID: 18974301] (Mouse)		Mouse
Poesen K, Lambrechts D, Van Damme P, Dhondt J, Bender F, Frank N, Bogaert E, Claes B, Heylen L, Verheyen A, Raes K, Tjwa M, Eriksson U, Shibuya M, Nuydens R, Van Den Bosch L, Meert T, D'Hooge R, Sendtner M, Robberecht W, Carmeliet P Novel role for vascular endothelial growth factor (VEGF) receptor-1 and its ligand VEGF-B in motor neuron degeneration. J. Neurosci., 2008-10-15;28(42):10451-9. 2008-10-15 [PMID: 18923022] (Rat)		Rat
Zhou CC, Zhang Y, Irani RA, Zhang H, Mi T, Popek EJ, Hicks MJ, Ramin SM, Kellems RE, Xia Y Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice. Nat. Med., 2008-07-27;14(8):855-62. 2008-07-27 [PMID: 18660815] (Mouse)		Mouse
Izumi-Nagai K, Nagai N, Ohgami K, Satofuka S, Ozawa Y, Tsubota K, Ohno S, Oike Y, Ishida S Inhibition of choroidal neovascularization with an anti-inflammatory carotenoid astaxanthin. Invest. Ophthalmol. Vis. Sci., 2008-04-01;49(4):1679-85. 2008-04-01 [PMID: 18385091] (Mouse)		Mouse
Xie B, Shen J, Dong A, Swaim M, Hackett SF, Wyder L, Worpenberg S, Barbieri S, Campochiaro PA An Adam15 amplification loop promotes vascular endothelial growth factor-induced ocular neovascularization. FASEB J., 2008-04-01;22(8):2775-83. 2008-04-01 [PMID: 18381816] (Mouse)		Mouse
Tsao PN, Chan FT, Wei SC, Hsieh WS, Chou HC, Su YN, Chen CY, Hsu WM, Hsieh FJ, Hsu SM Soluble vascular endothelial growth factor receptor-1 protects mice in sepsis. Crit. Care Med., 2007-08-01;35(8):1955-60. 2007-08-01 [PMID: 17568329] (Mouse)		Mouse
Shimojo N, Jesmin S, Zaedi S, Otsuki T, Maeda S, Yamaguchi N, Aonuma K, Hattori Y, Miyauchi T Contributory role of VEGF overexpression in endothelin-1-induced cardiomyocyte hypertrophy. Am. J. Physiol. Heart Circ. Physiol., 2007-03-16;293(1):H474-81. 2007-03-16 [PMID: 17369464] (Rat)		Rat
Hara A, Wada T, Furuichi K, Sakai N, Kawachi H, Shimizu F, Shibuya M, Matsushima K, Yokoyama H, Egashira K, Kaneko S Blockade of VEGF accelerates proteinuria, via decrease in nephrin expression in rat crescentic glomerulonephritis. Kidney Int., 2006-06-01;69(11):1986-95. 2006-06-01 [PMID: 16641924] (Transgenic Rat)		Transgenic Rat
Iemitsu M, Maeda S, Jesmin S, Otsuki T, Miyauchi T Exercise training improves aging-induced downregulation of VEGF angiogenic signaling cascade in hearts. Am. J. Physiol. Heart Circ. Physiol., 2006-04-14;291(3):H1290-8. 2006-04-14 [PMID: 16617130] (Rat)		Rat
Nagai N, Noda K, Urano T, Kubota Y, Shinoda H, Koto T, Shinoda K, Inoue M, Shiomi T, Ikeda E, Tsubota K, Suda T, Oike Y, Ishida S Selective suppression of pathologic, but not physiologic, retinal neovascularization by blocking the angiotensin II type 1 receptor. Invest. Ophthalmol. Vis. Sci., 2005-03-01;46(3):1078-84. 2005-03-01 [PMID: 15728568] (Mouse)		Mouse
Sako A, Kitayama J, Koyama H, Ueno H, Uchida H, Hamada H, Nagawa H Transduction of soluble Flt-1 gene to peritoneal mesothelial cells can effectively suppress peritoneal metastasis of gastric cancer. Cancer Res., 2004-05-15;64(10):3624-8. 2004-05-15 [PMID: 15150121] (Mouse)		Mouse
Maynard SE, Min JY, Merchan J, Lim KH, Mondal S, Stillman IE, Epstein FH, Karumanchi SA Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J. Clin. Invest., 2003-03-01;111(5):649-58. 2003-03-01 [PMID: 12618519] (Rat)		Rat
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Mouse VEGFR1/Flt-1 Quantikine ELISA Kit

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