Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Mouse gp130 DuoSet ELISA, 15 Plate
CD130 antigen
CD130
CDw130
DKFZp564F053
gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form
gp130
IL-6 receptor subunit beta
IL-6R subunit beta
IL-6RB
IL-6R-beta
IL6ST
interleukin 6 signal transducer (gp130, oncostatin M receptor)
interleukin receptor beta chain
interleukin-6 receptor subunit beta
Interleukin-6 signal transducer
Membrane glycoprotein 130
membrane glycoprotein gp130
Oncostatin-M receptor subunit alpha
Background
Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the classI cytokine receptor family. Binding of IL-6 or IL-11 to either the membrane-anchored or soluble IL-6 R or IL-11 R, respectively, initiates the association of IL-6 R (IL-11 R) with gp130. The complex then undergoes homodimerization and signal transduction. For other IL-6 family cytokines, such as LIF and OSM, signal transduction is similarly triggered by the heterodimerization of gp130 with LIFR or OSM R.