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MMP-24/MT5-MMP Antibody [Unconjugated]

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MMP-24 was detected in immersion fixed paraffin-embedded sections of human brain using Rabbit Anti-Human/Mouse MMP-24/MT5-MMP Polyclonal Antibody (Catalog # AB924) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Rabbit HRP-AEC Cell & Tissue Staining Kit (red; Catalog # CTS006) and counterstained with hematoxylin (blue). Specific labeling was localized to the cytoplasm of neurons. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.
MMP-24 was detected in immersion fixed paraffin-embedded sections of human brain using Rabbit Anti-Human/Mouse MMP-24/MT5-MMP Polyclonal Antibody (Catalog # AB924) at 15 µg/mL overnight at 4 °C. Tissue was stained ...read more
MMP-24 was detected in immersion fixed paraffin-embedded sections of human brain (astrocytoma) using Rabbit Anti-Human/Mouse MMP-24/ MT5-MMP Polyclonal Antibody (Catalog # AB924) at 15 µg/mL overnight at 4 °C. Tissue ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
LYOPH

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MMP-24/MT5-MMP Antibody [Unconjugated] Summary

Immunogen
E. coli-derived recombinant human MMP‑24/MT5-MMP
Specificity
Detects human and mouse MMP‑24/MT5-MMP in Western blots.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MMP24
Purity Statement
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunohistochemistry 5-15 ug/mL
  • Immunoprecipitation 25 ug/mL
  • Western Blot 1 ug/mL
Publications
Read Publication using
AB924 in the following applications:

  • ICC
    1 publication
  • IHC
    1 publication

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MMP-24/MT5-MMP Antibody [Unconjugated]

  • EC 3.4.24
  • EC 3.4.24.-
  • EC 3.4.24.80
  • matrix metallopeptidase 24 (membrane-inserted)
  • matrix metalloproteinase 24 (membrane-inserted)
  • matrix metalloproteinase-24
  • membrane-type 5 matrix metalloproteinase
  • Membrane-type matrix metalloproteinase 5
  • Membrane-type-5 matrix metalloproteinase
  • MMP24
  • MMP-24
  • MT5MMP
  • MT5-MMP
  • MT5-MMPMMP25
  • MT-MMP 5
  • MTMMP5
  • MT-MMP5

Background

The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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MMP-24/MT5-MMP
Antibody [Unconjugate
AB924
MMP-24/MT5-MMP Antibody [Unconjugated]
Species: Hu, Mu
Applications: WB, IHC, IP

Publications for MMP-24/MT5-MMP Antibody (AB924)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: ICC, IHC.


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Secondary Antibodies

 

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Bioinformatics

Gene Symbol MMP24