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Meprin alpha Subunit/MEP1A Antibody

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Western Blot: Meprin alpha Subunit/MEP1A Antibody [NBP1-32595] - (30 ug whole cell lysate) A431 7.5% SDS PAGE; antibody diluted at 1:1000

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Meprin alpha Subunit/MEP1A Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human Meprin alpha Subunit/MEP1A. The exact sequence is proprietary.
Localization
Membrane, Single-pass type I membrane protein
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MEP1A
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500-1:3000
Application Notes
IHC-P and ICC/IF reactivity reported in scientific literature (PMID: 23427141).
Theoretical MW
84 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using
NBP1-32595 in the following applications:

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 23427141). Rat (85%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
Preservative
0.01% Thimerosal
Purity
Antigen Affinity-purified

Alternate Names for Meprin alpha Subunit/MEP1A Antibody

  • bA268F1.1 (meprin A alpha (PABA peptide hydrolase))
  • EC 3.4.24
  • EC 3.4.24.18
  • endopeptidase-2
  • MEP1A
  • meprin A subunit alpha
  • meprin A, alpha (PABA peptide hydrolase)
  • Meprin alpha Subunit
  • N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha
  • PABA peptide hydrolase
  • PPH alpha
  • PPHA

Background

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes and in leukocytes and certain cancer cells. Mature meprins are oligomers of evolutionarily related, separately encoded alpha and/or beta subunits. Homooligomers of meprin-alpha are secreted; oligomers containing meprin-beta are associated with the plasma membrane. Substrates include bioactive peptides and extracellular matrix proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for Meprin alpha Subunit/MEP1A Antibody (NBP1-32595)(1)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 2 applications: ICC/IF, IHC-P.


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(1)
IHC-P
(1)
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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol MEP1A
Entrez
Uniprot