Immunocytochemistry/ Immunofluorescence: MEIS2 Antibody [NBP1-81669] - Staining of human cell line A-431 shows localization to nucleoplasm & cytosol. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: MEIS2 Antibody [NBP1-81669] - Staining of human liver shows low positivity in hepatocytes as expected.
Orthogonal Strategies: Immunohistochemistry-Paraffin: MEIS2 Antibody [NBP1-81669] - Staining of human cerebral cortex shows strong nuclear positivity in neurons.
Immunohistochemistry-Paraffin: MEIS2 Antibody [NBP1-81669] - Staining of human endometrium shows moderate nuclear positivity in glandular and stromal cells.
Immunohistochemistry-Paraffin: MEIS2 Antibody [NBP1-81669] - Staining of human prostate shows strong nuclear positivity in glandular and smooth muscle cells.
This antibody was developed against Recombinant Protein corresponding to amino acids: LEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGHASQSGDNSSEQGDGLDNSV
Predicted Species
Rat (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MEIS2
Purity
Immunogen affinity purified
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Mouse reactivity reported in scientific literature (PMID: 24854274).
Packaging, Storage & Formulations
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for MEIS2 Antibody
Meis (mouse) homolog 2
Meis homeobox 2
Meis1, myeloid ecotropic viral integration site 1 homolog 2 (mouse)
Meis1-related gene 1
MGC2820
myeloid ecotropic viral integration site 1 homolog 2
TALE homeobox protein Meis2
Background
MEIS2 encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs. Multiple transcript variants encoding distinct isoforms have been described for this gene.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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