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MAP4K6 Antibody

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Western Blot: MAP4K6 Antibody [NBP2-17220] - Sample (30 ug of whole cell lysate) A: MCF-7 5% SDS PAGE gel, diluted at 1:1000.

Product Details

Summary
Reactivity Hu, Mu, Rt, BvSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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MAP4K6 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human MAP4K6. The exact sequence is proprietary.
Predicted Species
Mouse (98%), Rat (98%), Bovine (98%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MINK1
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
Theoretical MW
150 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Xenopus laevis (89%), Zebrafish (87%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7), 20% Glycerol, 1% BSA
Preservative
0.01% Thimerosal
Purity
Antigen Affinity-purified

Alternate Names for MAP4K6 Antibody

  • B55
  • EC 2.7.11
  • GCK family kinase MiNK
  • hMINK
  • hMINKbeta
  • MAP4K6EC 2.7.11.1
  • MAPK/ERK kinase kinase kinase 6
  • MEK kinase kinase 6
  • MGC21111
  • MINKMEKKK 6
  • Misshapen/NIK-related kinase
  • misshapen-like kinase 1 (zebrafish)
  • misshapen-like kinase 1
  • Mitogen-activated protein kinase kinase kinase kinase 6
  • serine/threonine protein kinase
  • YSK2
  • ZC3

Background

This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Research Areas for MAP4K6 Antibody (NBP2-17220)

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Blogs on MAP4K6.

The NLRP3 Inflammasome: Macrophage Activator & Pathology Driver
By Victoria Osinski, PhDWhat is the NLRP3 Inflammasome?With its critical role in innate immunity, the nucleotide-binding oligomerization domain-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome ...  Read full blog post.

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Bioinformatics

Gene Symbol MINK1
Uniprot