Western Blot: MAGED2 Antibody [NBP2-24694] - Analysis of MAGE-D1/2 in A375 cell lysate using NBP2-24694 at 5 ug/ml. Goat anti-rabbit Ig HRP secondary antibody and Picotect ECL substrate solution were used for this test.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.2 ml PBS and 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A purified
Alternate Names for MAGED2 Antibody
11B6MAGE-D2 antigen
BCG-1
BCG1MAGEDHCA10
breast cancer associated gene 1
Breast cancer-associated gene 1 protein
hepatocellular carcinoma associated protein
hepatocellular carcinoma-associated protein HCA10
Hepatocellular carcinoma-associated protein JCL-1
JCL-1
MAGE-D2
melanoma antigen family D, 2
melanoma-associated antigen D2
MGC8386
Background
MAGE-D2, also known as Melanoma-associated antigen D2, belongs to the melanoma antigen encoding gene (MAGE) family with a MAGE domain. Rat and mouse orthologues have been isolated. Compared to other proteins (MAGE-A, MAGE- B and MAGE-C clusters) MAGE-D2 is expressed ubiquitously. This intracellular protein shows high expression in specific brain regions and in the interstitium of testes. Though the exact function of this protein is yet to be deduced, MAGE-D2 is considered as a hot spot for X-linked mental retardation. Research reveals that MAGE-D2 might have some role in breast and gastric cancer, as well as in hepatocellular carcinoma. MAGE-D2 is also known to interact physically with p53 and modify its activity, thus acting as a p53-dissociator.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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