Livin Antibody

The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Flow Cytometry Control.

Showing Publications 1 - 2 of 2.

Publications using NB300-941	Applications	Species
Schatton T, Schutte U, Frank NY et al. Modulation of T-cell activation by malignant melanoma initiating cells. Cancer Res. 2010-01-15 [PMID: 20068175] (Flow Cytometry Control, Human) Details: Livin/BIRC7/kIAP (IMG-3366). Flow (intracellular): Human malignant melanoma cell line, Fig 1D.	Flow Cytometry Control	Human
Kasof GM, Gomes BC. Livin, a novel inhibitor of apoptosis protein family member. J Biol Chem 2001-02-02 [PMID: 11024045]

Array NB300-941

• Livin Antibodies
• Livin ELISA Kit
• Livin Lysates
• Livin Proteins
• Livin Proteins and Enzyme