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LATS2 Antibody (OTI2D3) [DyLight 488]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clone
OTI2D3
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-71829AF350
Alexa Fluor 405
NBP2-71829AF405
Alexa Fluor 488
NBP2-71829AF488
Alexa Fluor 532
NBP2-71829AF532
Alexa Fluor 594
NBP2-71829AF594
Alexa Fluor 647
NBP2-71829AF647
Alexa Fluor 700
NBP2-71829AF700
Alexa Fluor 750
NBP2-71829AF750
Allophycocyanin
NBP2-71829APC
Biotin
NBP2-71829B
CoraFluor 1
NBP2-71829CL1
DyLight 350
NBP2-71829UV
DyLight 405
NBP2-71829V
DyLight 550
NBP2-71829R
DyLight 594
NBP2-71829DL594
DyLight 650
NBP2-71829C
DyLight 680
NBP2-71829FR
DyLight 755
NBP2-71829IR
FITC
NBP2-71829F
HRP
NBP2-71829H
Janelia Fluor 525
NBP2-71829JF525
Janelia Fluor 669
NBP2-71829JF669
PE
NBP2-71829PE
PerCP
NBP2-71829PCP
Unconjugated
NBP2-45612
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-45612
Azide and BSA Free
NBP2-71829
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LATS2 Antibody (OTI2D3) [DyLight 488] Summary

Immunogen
Recombinant protein fragment corresponding to amino acids 1-237 of human LATS2 (NP_055387) produced in E.coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
LATS2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for LATS2 Antibody (OTI2D3) [DyLight 488]

  • EC 2.7.11
  • EC 2.7.11.1
  • FLJ13161
  • Kinase phosphorylated during mitosis protein
  • KPM
  • Large tumor suppressor homolog 2
  • LATS (large tumor suppressor, Drosophila) homolog 2
  • LATS, large tumor suppressor, homolog 2 (Drosophila)
  • serine/threonine kinase KPM
  • Serine/threonine-protein kinase kpm
  • serine/threonine-protein kinase LATS2
  • Warts-like kinase

Background

LATS2 encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NBP2-71829G
LATS2 Antibody (OTI2D3) [DyLight 488]
Species: Hu, Mu, Rt
Applications: WB

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol LATS2