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Latrophilin 2/LPHN2 Antibody - BSA Free

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Immunohistochemistry-Paraffin: Latrophilin 2/LPHN2 Antibody [NLS1133] - Analysis of anti-LPHN2 antibody with human ovary, graafian follicle.
Immunohistochemistry-Paraffin: Latrophilin 2/LPHN2 Antibody [NLS1133] - Analysis of anti-LPHN2 antibody with human ovary, graafian follicle.

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bt, Bv, Ca, Eq, Pm, Rb, Ma-Op, PmSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.0 mg/ml

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Latrophilin 2/LPHN2 Antibody - BSA Free Summary

Description
Product can be stored undiluted at 4C for up to 1 month.
Immunogen
Synthetic 16 amino acid peptide from N-terminal extracellular domain of human Latrophilin 2/LPHN2.
Epitope
N-Terminus extracellular domain
Localization
Integral membrane protein.
Specificity
Human LPHN2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Primate (100%), Opossum (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
LPHN2
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 7 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Monkey (100%), Marmoset (94%).

Packaging, Storage & Formulations

Storage
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Latrophilin 2/LPHN2 Antibody - BSA Free

  • ADGRL2
  • Calcium-independent alpha-latrotoxin receptor 2
  • CIRL2
  • CIRL-2
  • CL2
  • KIAA0786
  • Latrophilin 2
  • Latrophilin homolog 1
  • latrophilin homolog 2 (cow)
  • latrophilin-2
  • LEC1
  • LEC1LPHH1latrophilin 1
  • lectomedin-1
  • LPHH1
  • LPHN2

Background

LPHN2 is an Orphan-B Receptor that binds alpha-latrotoxin, a potent presynaptic neurotoxin present in the venom of the black widow spider, in a Ca2+-independent manner. As with the other two latrophilins, it shares homology with lectin, olfactomedin, and transmembrane domains, and possesses variable C-termini and various alternative-splice sites. LPHN2 is endoproteolytically cleaved at the end of the GPS domain, and the two subunits remain non-covantely linked as a heterodimer. LPHN2 has been reported to be expressed in brain, breast, placenta, kidney, spleen, ovary, heart, and lung. ESTs have been isolated from a wide variety of tissue libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Latrophilin
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NLS1133
Latrophilin 2/LPHN2 Antibody - BSA Free
Species: Hu, Mu, Rt, Po, Bt, Bv, Ca, Eq, Pm, Rb, Ma-Op, Pm
Applications: IHC

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Product General Protocols

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Bioinformatics

Gene Symbol LPHN2
Entrez