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Latrophilin 2/LPHN2 Antibody (1030202) [mFluor Violet 450 SE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, CyTOF-ready
Clone
1030202
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 450 SE

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Latrophilin 2/LPHN2 Antibody (1030202) [mFluor Violet 450 SE] Summary

Immunogen
Human Latrophilin 2/LPHN2 synthetic peptide
Accession # O95490
Specificity
Detects human Latrophilin 2/LPHN2 in direct ELISAs.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Latrophilin 2/LPHN2 Antibody (1030202) [mFluor Violet 450 SE]

  • ADGRL2
  • Calcium-independent alpha-latrotoxin receptor 2
  • CIRL2
  • CIRL-2
  • CL2
  • KIAA0786
  • Latrophilin 2
  • Latrophilin homolog 1
  • latrophilin homolog 2 (cow)
  • latrophilin-2
  • LEC1
  • LEC1LPHH1latrophilin 1
  • lectomedin-1
  • LPHH1
  • LPHN2

Background

Latrophilin-2 is an Orphan-B Receptor that binds alpha-latrotoxin, a potent presynaptic neurotoxin present in the venom of the black widow spider, in a Ca2+-independent manner. As with the other two latrophilins, it shares homology with lectin, olfactomedin, and transmembrane domains, and possesses variable C-termini and various alternative-splice sites. Latrophilin-2 is endoproteolytically cleaved at the end of the GPS domain, and the two subunits remain non-covantely linked as a heterodimer. Latrophilin-2 has been reported to be expressed in brain, breast, placenta, kidney, spleen, ovary, heart, and lung. ESTs have been isolated from a wide variety of tissue libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Array FAB105881MFV450

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