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Latrophilin 2/LPHN2 Antibody (1030202) [DyLight 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, CyTOF-ready
Clone
1030202
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

Order Details

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Latrophilin 2/LPHN2 Antibody (1030202) [DyLight 405] Summary

Immunogen
Human Latrophilin 2/LPHN2 synthetic peptide
Accession # O95490
Specificity
Detects human Latrophilin 2/LPHN2 in direct ELISAs.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Latrophilin 2/LPHN2 Antibody (1030202) [DyLight 405]

  • ADGRL2
  • Calcium-independent alpha-latrotoxin receptor 2
  • CIRL2
  • CIRL-2
  • CL2
  • KIAA0786
  • Latrophilin 2
  • Latrophilin homolog 1
  • latrophilin homolog 2 (cow)
  • latrophilin-2
  • LEC1
  • LEC1LPHH1latrophilin 1
  • lectomedin-1
  • LPHH1
  • LPHN2

Background

Latrophilin-2 is an Orphan-B Receptor that binds alpha-latrotoxin, a potent presynaptic neurotoxin present in the venom of the black widow spider, in a Ca2+-independent manner. As with the other two latrophilins, it shares homology with lectin, olfactomedin, and transmembrane domains, and possesses variable C-termini and various alternative-splice sites. Latrophilin-2 is endoproteolytically cleaved at the end of the GPS domain, and the two subunits remain non-covantely linked as a heterodimer. Latrophilin-2 has been reported to be expressed in brain, breast, placenta, kidney, spleen, ovary, heart, and lung. ESTs have been isolated from a wide variety of tissue libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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