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Latrophilin 2/LPHN2 Antibody (1030202) [Allophycocyanin/Cy7]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
1030202
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin/Cy7

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Latrophilin 2/LPHN2 Antibody (1030202) [Allophycocyanin/Cy7] Summary

Immunogen
Human Latrophilin 2/LPHN2 synthetic peptide
Accession # O95490
Specificity
Detects human Latrophilin 2/LPHN2 in direct ELISAs.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for Latrophilin 2/LPHN2 Antibody (1030202) [Allophycocyanin/Cy7]

  • ADGRL2
  • Calcium-independent alpha-latrotoxin receptor 2
  • CIRL2
  • CIRL-2
  • CL2
  • KIAA0786
  • Latrophilin 2
  • Latrophilin homolog 1
  • latrophilin homolog 2 (cow)
  • latrophilin-2
  • LEC1
  • LEC1LPHH1latrophilin 1
  • lectomedin-1
  • LPHH1
  • LPHN2

Background

Latrophilin-2 is an Orphan-B Receptor that binds alpha-latrotoxin, a potent presynaptic neurotoxin present in the venom of the black widow spider, in a Ca2+-independent manner. As with the other two latrophilins, it shares homology with lectin, olfactomedin, and transmembrane domains, and possesses variable C-termini and various alternative-splice sites. Latrophilin-2 is endoproteolytically cleaved at the end of the GPS domain, and the two subunits remain non-covantely linked as a heterodimer. Latrophilin-2 has been reported to be expressed in brain, breast, placenta, kidney, spleen, ovary, heart, and lung. ESTs have been isolated from a wide variety of tissue libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Array FAB105881APCCY7

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