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LAR/PTPRF Antibody (S165-38) [DyLight 488]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF
Clone
S165-38
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 405
NBP2-42172AF405
Alexa Fluor 488
NBP2-42172AF488
Alexa Fluor 647
NBP2-42172AF647
Alexa Fluor 700
NBP2-42172AF700
Biotin
NBP2-42172B
DyLight 350
NBP2-42172UV
DyLight 405
NBP2-42172V
DyLight 550
NBP2-42172R
DyLight 650
NBP2-42172C
DyLight 680
NBP2-42172FR
DyLight 755
NBP2-42172IR
FITC
NBP2-42172F
HRP
NBP2-42172H
Janelia Fluor 549
NBP2-42172JF549
Janelia Fluor 646
NBP2-42172JF646
Unconjugated
NBP2-42172
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LAR/PTPRF Antibody (S165-38) [DyLight 488] Summary

Immunogen
Fusion protein amino acids 1315-1607 (cytoplasmic C-terminus) of human LAR. 97% identical in both rat and mouse. >80% identity with PTPRD and PTPRS. >50% identity with PTPRM and PTPRK.
Localization
Membrane
Specificity
Greater then 80% identity with PTPRD and PTPRS. Greater then 50% identity with PTPRM and PTPRK.Detects approx 85kDa (full length protein is 210 kDa -smaller due to proteolysis into P-subunit containing transmembrane and intracellular domains.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
PTPRF
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for LAR/PTPRF Antibody (S165-38) [DyLight 488]

  • LAR
  • LCA-homolog
  • protein tyrosine phosphatase, receptor type, F
  • PTPRF
  • receptor type, F polypeptide
  • receptor-linked protein-tyrosine phosphatase LAR
  • receptor-type tyrosine-protein phosphatase F

Background

PTPRF, also known as Receptor-type tyrosine-protein phosphatase F, is a 213kDa 1907 amino acid protein with a shorter 212kDa 1898 isoform. PTPRF is a member of the protein tyrosine phosphatase (PTP) family and functions as a possible cell adhesion receptor. Research is being conducted on PTPRF in relation to melanoma, carcinoma, retinitis, thyroid carcinoma, ureterocele, lung cancer, breast cancer and obesity. PTPRF is linked to the cell adhesion and insulin signaling pathways where it interacts with CAV1, PRPF40A, SKIL, ZNF512B and JUP.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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LAR/PTPRF Antibody
(S165-38) [DyLight 48 ...
NBP2-42172G
LAR/PTPRF Antibody (S165-38) [DyLight 488]
Species: Hu, Mu, Rt
Applications: WB, ICC/IF

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Bioinformatics

Gene Symbol PTPRF