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LAIR1 Antibody (113) [DyLight 405]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, Flow, IP
Clone
113
Clonality
Monoclonal
Host
Armenian Hamster
Conjugate
DyLight 405

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-43324AF350
Alexa Fluor 405
NBP1-43324AF405
Alexa Fluor 488
NBP1-43324AF488
Alexa Fluor 532
NBP1-43324AF532
Alexa Fluor 594
NBP1-43324AF594
Alexa Fluor 647
NBP1-43324AF647
Alexa Fluor 700
NBP1-43324AF700
Alexa Fluor 750
NBP1-43324AF750
Allophycocyanin
NBP1-43324APC
Allophycocyanin/Cy7
NBP1-43324APCCY7
Biotin
NBP1-43324B
CoraFluor 1
NBP1-43324CL1
DyLight 350
NBP1-43324UV
DyLight 488
NBP1-43324G
DyLight 550
NBP1-43324R
DyLight 594
NBP1-43324DL594
DyLight 650
NBP1-43324C
DyLight 680
NBP1-43324FR
DyLight 755
NBP1-43324IR
FITC
NBP1-43324F
HRP
NBP1-43324H
Janelia Fluor 525
NBP1-43324JF525
Janelia Fluor 549
NBP1-43324JF549
Janelia Fluor 646
NBP1-43324JF646
Janelia Fluor 669
NBP1-43324JF669
PE
NBP1-43324PE
PE/Atto594
NBP1-43324PEATT594
PE/Cy5.5
NBP1-43324PECY55
PE/Cy7
NBP1-43324PECY7
PerCP
NBP1-43324PCP
Unconjugated
NBP1-43324
mFluor Violet 450 SE
NBP1-43324MFV450
mFluor Violet 500 SE
NBP1-43324MFV500
mFluor Violet 610 SE
NBP1-43324MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-43324
BSA Free
NBP1-43324
BSA Free
NBP1-43324-0.05mg
BSA Free
NBP1-43324-0.025mg
Novus Biologicals offers 100% Guarantee

LAIR1 Antibody (113) [DyLight 405] Summary

Immunogen
The immunogen for this antibody was CD305.
Isotype
IgG
Clonality
Monoclonal
Host
Armenian Hamster
Gene
LAIR1
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunoprecipitation
  • Western Blot
Application Notes
This 113 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.25 ug per test. A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 uL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for LAIR1 Antibody (113) [DyLight 405]

  • CD305 antigen
  • CD305
  • CD305leukocyte-associated Ig-like receptor 1
  • HLAIR1
  • LAIR1
  • LAIR-1
  • leukocyte-associated immunoglobulin-like receptor 1

Background

LAIR1 is a transmembrane glycoprotein(approx. 32kDa) expressed on the majority of human peripheral blood mononuclear leukocytes including T cells, B cells, NK cells, macrophages and dendritic cells. LAIR1 recruits SHP1 and SHP2 tyrosine phosphatases upon activation, and cross-linking of the LAIR1 molecule on NK cells results in strong inhibition of NK cell mediated cytotoxicity. This clone is reported to inhibit NK cell triggering via CD16 molecules.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol LAIR1