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LAIR1 Antibody (113) [FITC]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, Flow, IP
Clone
113
Clonality
Monoclonal
Host
Armenian Hamster
Conjugate
FITC

Order Details

LAIR1 Antibody (113) [FITC] Summary

Immunogen
The immunogen for this antibody was CD305.
Isotype
IgG
Clonality
Monoclonal
Host
Armenian Hamster
Gene
LAIR1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Alternate Names for LAIR1 Antibody (113) [FITC]

  • CD305 antigen
  • CD305
  • CD305leukocyte-associated Ig-like receptor 1
  • HLAIR1
  • LAIR1
  • LAIR-1
  • leukocyte-associated immunoglobulin-like receptor 1

Background

LAIR1 is a transmembrane glycoprotein(approx. 32kDa) expressed on the majority of human peripheral blood mononuclear leukocytes including T cells, B cells, NK cells, macrophages and dendritic cells. LAIR1 recruits SHP1 and SHP2 tyrosine phosphatases upon activation, and cross-linking of the LAIR1 molecule on NK cells results in strong inhibition of NK cell mediated cytotoxicity. This clone is reported to inhibit NK cell triggering via CD16 molecules.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol LAIR1