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LAIR1 Antibody (113) [DyLight 488]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, Flow, IP
Clone
113
Clonality
Monoclonal
Host
Armenian Hamster
Conjugate
DyLight 488

Order Details

LAIR1 Antibody (113) [DyLight 488] Summary

Immunogen
The immunogen for this antibody was CD305.
Isotype
IgG
Clonality
Monoclonal
Host
Armenian Hamster
Gene
LAIR1
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for LAIR1 Antibody (113) [DyLight 488]

  • CD305 antigen
  • CD305
  • CD305leukocyte-associated Ig-like receptor 1
  • HLAIR1
  • LAIR1
  • LAIR-1
  • leukocyte-associated immunoglobulin-like receptor 1

Background

CD305 or Leukocyte-associated Ig-like receptor-1 (LAIR-1) is a 46 kD cell surface molecule that functions as an inhibitory collagen-receptor on the majority of cells of the immune system. The mouse LAIR-1 molecule is expressed primarily on monocytes/macrophages and also on T cells, NK cells and dendritic cells. Unlike human B cells , mouse B cells do not express LAIR-1. The cytoplasmic tail of mouse LAIR-1 can be phosphorylated leading to the recruitment of SH2-containing tyrosine phosphatase(SHP)-2 and C-terminal Src kinase.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol LAIR1