Western Blot: Laforin/EPM2A Antibody [NBP2-24474] - Analysis of EPM2A in human heart lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse heart and 4) rat heart lysate using this antibody. 25 ug/ml, ...read more
Immunohistochemistry-Paraffin: Laforin/EPM2A Antibody [NBP2-24474] - Formalin-fixed, paraffin-embedded human heart stained with EPM2A antibody at 10 ug/ml. Staining of formalin-fixed tissues is enhanced by boiling ...read more
Immunogen displays the following percentage of sequence identity for non-tested species: Zebrafish (87%). Bovine data from PMID: 32146261.
Packaging, Storage & Formulations
Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.2 ml PBS and 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified
Alternate Names for Laforin/EPM2A Antibody
EC 3.1.3.16
EC 3.1.3.48
epilepsy, progressive myoclonus type 2, Lafora disease (laforin)
epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPM2
EPM2A
Lafora PTPase
Laforin
LAFPTPase
LD
LDE
MELF
Background
EPM2A encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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