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Laforin/EPM2A Antibody

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Western Blot: Laforin/EPM2A Antibody [NBP2-24474] - Analysis of EPM2A in human heart lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse heart and 4) rat heart lysate using this antibody. 25 ug/ml, ...read more
Immunohistochemistry-Paraffin: Laforin/EPM2A Antibody [NBP2-24474] - Formalin-fixed, paraffin-embedded human heart stained with EPM2A antibody at 10 ug/ml. Staining of formalin-fixed tissues is enhanced by boiling ...read more

Product Details

Summary
Reactivity Hu, Bv, Mu, Rt, Ca, Ch, Pm, Eq, Ma-Op, Pm, RM, XpSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

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Laforin/EPM2A Antibody Summary

Immunogen
A portion of amino acids 80-130 of human Laforin/EPM2A was used as the immunogen for the antibody.
Predicted Species
Mouse (100%), Rat (100%), Chicken (93%), Canine (100%), Xenopus (93%), Primate (93%), Equine (100%), Rhesus Macaque (93%), Opossum (93%), Chimpanzee (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
EPM2A
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10 ug/ml
  • Western Blot 0.25-0.50 ug/ml
Publications
Read Publications using
NBP2-24474 in the following applications:

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Zebrafish (87%). Bovine data from PMID: 32146261.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.2 ml PBS and 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Laforin/EPM2A Antibody

  • EC 3.1.3.16
  • EC 3.1.3.48
  • epilepsy, progressive myoclonus type 2, Lafora disease (laforin)
  • epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
  • EPM2
  • EPM2A
  • Lafora PTPase
  • Laforin
  • LAFPTPase
  • LD
  • LDE
  • MELF

Background

EPM2A encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Laforin/EPM2A Antibody (NBP2-24474)(3)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol EPM2A
Uniprot