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Intersectin 2 Antibody

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Western Blot: Intersectin 2 Antibody [NBP2-86680] - WB Suggested Anti-ITSN2 Antibody. Titration: 1.0 ug/ml. Positive Control: HepG2 Whole Cell
Western Blot: Intersectin 2 Antibody [NBP2-86680] - WB Suggested Anti-ITSN2 Antibody. Titration: 1.0 ug/ml. Positive Control: HepG2 Whole Cell

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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Intersectin 2 Antibody Summary

Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human Intersectin 2. Peptide sequence: TFTEGEEILVTQKDGEWWTGSIGDRSGIFPSNYVKPKDQESFGSASKSGA The peptide sequence for this immunogen was taken from within the described region.
Clonality
Polyclonal
Host
Rabbit
Gene
ITSN2
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1.0 ug/ml

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for Intersectin 2 Antibody

  • intersectin 2
  • KIAA1256SH3 domain-containing protein 1B
  • PRO2015
  • SH3 domain protein 1B
  • SH3P18-like WASP associated protein
  • SH3P18SH3D1Bintersectin-2
  • SWA
  • SWAPSH3P18-like WASP-associated protein

Background

Intersectin-2 is a cytoplasmic adapter protein that may provide a link between the actin assembly machinery and the endocytic membrance traffic, as well a control the production of clathrin-coated vesicles in terms of their invagination of budding. Intersectin-2 has four isoforms, with lengths of 1697, 1670, 1249, and 1192 amino acids and weights of 193, 190, 141, and 135 kDa respectively. Studies have been conducted on diseases and disorders related to this protein including Wiskott-Aldrich syndrome, dermatitis, sarcoma, schizophrenia, spasticity, pancreatitis, and pancreatic cancer. Intersectin-2 has also been known to have interactions with BCCIP, PTN, TBL3, MAP4K3, and SEMA6A in pathways such as the regulation of CDC42 activity pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ITSN2