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Importin alpha 3/KPNA4 Antibody

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Western Blot: Importin alpha 3/KPNA4 Antibody [NB100-1374] - Staining of Human Ovary (A), Mouse Testes (B) with antibody at 0.1 ug/mL, Mouse Ovary (C) with antibody at 0.3 ug/mL and Rat Testes (D) lysate with antibody ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, CaSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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Importin alpha 3/KPNA4 Antibody Summary

Immunogen
Peptide with sequence C-NSSANVPTEGFQF corresponding to C-Terminus according to NP_002259.1.
Localization
Cytoplasmic and Nuclear
Predicted Species
Canine (100%), Bovine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
KPNA4
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Peptide ELISA Detection limit 1:28000
  • Western Blot 0.03 - 0.3 ug/mL
Application Notes
Approx 55 kDa band observed in Human and Mouse Ovary and in Mouse Testis lysates, and approx 60 kDa in Rat Testis lysates (calculated MW of 57.9 kDa according to Human NP_002259.1, Mouse NP_032493.1 and Rat NP_001014793.1).
Control
Human Testis Whole Tissue Lysate (Adult Whole Normal)
Importin alpha 3/KPNA4 Overexpression Lysate
Control Peptide
Importin alpha 3/KPNA4 Peptide (NB100-1374PEP)
Publications
Read Publications using
NB100-1374 in the following applications:

  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Importin alpha 3/KPNA4 Antibody

  • Importin alpha 3
  • Importin alpha Q1
  • importin subunit alpha-4
  • importin-alpha-Q1
  • IPOA3
  • karyopherin alpha 4 (importin alpha 3)
  • KPNA4
  • MGC12217
  • MGC26703
  • Qip1
  • QIP12
  • QIP1Karyopherin subunit alpha-4
  • SRP3

Background

The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Importin alpha 3/KPNA4 Antibody (NB100-1374)(2)

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Bioinformatics

Gene Symbol KPNA4
Entrez
Uniprot