Western Blot: Importin alpha 3/KPNA4 Antibody [NB100-1374] - Staining of Human Ovary (A), Mouse Testes (B) with antibody at 0.1 ug/mL, Mouse Ovary (C) with antibody at 0.3 ug/mL and Rat Testes (D) lysate with antibody ...read more
Approx 55 kDa band observed in Human and Mouse Ovary and in Mouse Testis lysates, and approx 60 kDa in Rat Testis lysates (calculated MW of 57.9 kDa according to Human NP_002259.1, Mouse NP_032493.1 and Rat NP_001014793.1).
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified
Alternate Names for Importin alpha 3/KPNA4 Antibody
Importin alpha 3
Importin alpha Q1
importin subunit alpha-4
importin-alpha-Q1
IPOA3
karyopherin alpha 4 (importin alpha 3)
KPNA4
MGC12217
MGC26703
Qip1
QIP12
QIP1Karyopherin subunit alpha-4
SRP3
Background
The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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