The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.
![Western Blot Importin alpha 3/KPNA4 Antibody (843124) [Unconjugated]](http://images.novusbio.com/fullsize2/Importin_alpha_3_MAB8204_Western_Blot_14656.jpg)
![Simple Western Importin alpha 3/KPNA4 Antibody (843124) [Unconjugated]](http://images.novusbio.com/fullsize2/Importin_alpha_3_MAB8204_Simple_Western_17261.jpg)
