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IL-5R alpha/CD125 Antibody (26815) [DyLight 755]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow
Clone
26815
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 755

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IL-5R alpha/CD125 Antibody (26815) [DyLight 755] Summary

Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL‑5 R alpha /CD125
Asp21-Arg335
Specificity
Detects human IL-5 R alpha /CD125 in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross‑react with recombinant human (rh) IL-5 R beta , rhIL-9 R, rhIL-4 R, rmIL-5 R alpha , or rhIL-13 R alpha 1.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
IL5RA
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for IL-5R alpha/CD125 Antibody (26815) [DyLight 755]

  • CD125 antigen
  • CD125
  • CDw125CD125
  • HSIL5R3
  • IL-5 R alpha
  • IL-5 receptor subunit alpha
  • IL5R alpha
  • IL-5R subunit alpha
  • IL5R
  • IL5RA
  • IL-5Ra
  • IL-5R-alpha
  • interleukin 5 receptor type 3
  • interleukin 5 receptor, alpha
  • interleukin-5 receptor alpha chain
  • interleukin-5 receptor alpha subunit
  • interleukin-5 receptor subunit alpha
  • MGC26560

Background

The protein encoded by the IL5RA gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol IL5RA