IL-24 Antibody Summary
Immunogen |
E. coli-derived recombinant mouse IL‑24 Gln27-Leu181 Accession # Q925S4.1 |
Specificity |
Detects mouse IL-24 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human IL-24 is observed. |
Source |
N/A |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Goat |
Gene |
IL24 |
Purity Statement |
Antigen Affinity-purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry 5-15 ug/mL
- Western Blot 0.1 ug/mL
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Publications |
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Packaging, Storage & Formulations
Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
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Buffer |
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
Preservative |
No Preservative |
Concentration |
LYOPH |
Reconstitution Instructions |
Reconstitute at 0.2 mg/mL in sterile PBS. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for IL-24 Antibody
Background
Mouse IL-24, also known as melanoma differentiation-associated gene 7
(MDA-7) and Th2-specific cytokine FISP, is a 27 kDa secreted
glycoprotein that is a member of the IL-10 family. It is synthesized as
a precursor with a large pro-region that is removed to generate a 155
aa mature protein. Mature mouse IL-24 shares 84% and 69% amino acid
identity with rat and human IL-24, respectively.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for IL-24 Antibody (AF2786)(3)
Showing Publications 1 -
3 of 3.
Publications using AF2786 |
Applications |
Species |
Christopher Sie, Ravi Kant, Christian Peter, Andreas Muschaweckh, Monika Pfaller, Lucy Nirschl et al. IL-24 intrinsically regulates Th17 cell pathogenicity in mice Journal of Experimental Medicine 2022-08-01 [PMID: 35819408] |
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Hsiao-Hsuan Wang, Jian-Hao Huang, Min-Hao Sue, Wei-Chih Ho, Yu-Hsiang Hsu, Kung-Chao Chang et al. Interleukin-24 protects against liver injury in mouse models EBioMedicine 2021-02-01 [PMID: 33508745] |
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Wai Po Chong, Mary J. Mattapallil, Kumarkrishna Raychaudhuri, So Jin Bing, Sihan Wu, Yajie Zhong et al. The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24 Immunity 2020-08-01 [PMID: 32673565] |
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