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IL-24 Antibody (MM0398-6F48) [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
MM0398-6F48
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

Order Details

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IL-24 Antibody (MM0398-6F48) [Biotin] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Immunogen
Human recombinant IL-24
Isotype
IgG2
Clonality
Monoclonal
Host
Mouse
Gene
IL24
Purity
Protein G purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for IL-24 Antibody (MM0398-6F48) [Biotin]

  • C49A
  • FISP
  • IL10B
  • IL24
  • IL-24
  • interleukin 24
  • MDA-7
  • MDA7MOB5
  • melanocyte-associated Mda-7
  • melanoma differentiation association protein 7
  • Melanoma differentiation-associated gene 7 protein
  • MOB-5
  • ST16
  • ST16interleukin-24
  • suppression of tumorigenicity 16 (melanoma differentiation)
  • Suppression of tumorigenicity 16 protein

Background

Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol IL24