Home » IL-17RA/IL-17R » IL-17RA/IL-17R Antibodies » IL-17RA/IL-17R Antibody (133617) [Phycoerythrin]
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IL-17RA/IL-17R Antibody (133617) [Phycoerythrin]

 (8 Publications)
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K562 human chronic myelogenous leukemia cell line was stained with Mouse Anti-Human IL-17 R PE-conjugated Monoclonal Antibody (Catalog # FAB177P, filled histogram) or isotype control antibody (IC002P, open histogram). View our protocol for Staining Membrane-associated Proteins.
K562 human chronic myelogenous leukemia cell line was stained with Mouse Anti-Human IL-17 R PE-conjugated Monoclonal Antibody (Catalog # FAB177P, filled histogram) or isotype control antibody (IC002P, open histogram). ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
133617
Clonality
Monoclonal
Host
Mouse
Conjugate
Phycoerythrin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB177U-100UG
Alexa Fluor 405
FAB177V-100UG
Alexa Fluor 488
FAB177G-100UG
Alexa Fluor 532
FAB177X
Alexa Fluor 594
FAB177T-100UG
Alexa Fluor 647
FAB177R-100UG
Alexa Fluor 700
FAB177N-025
Alexa Fluor 700
FAB177N-100
Alexa Fluor 750
FAB177S-100UG
Allophycocyanin
FAB177A-100
Allophycocyanin
FAB177A-025
Allophycocyanin/Cy7
FAB177APCCY7
Biotin
FAB177B
CoraFluor 1
FAB177CL1
DyLight 350
FAB177D
DyLight 405
FAB177E
DyLight 488
FAB177K
DyLight 550
FAB177L
DyLight 594
FAB177M
DyLight 650
FAB177W
DyLight 680
FAB177Y
DyLight 755
FAB177Z
HRP
FAB177H
Janelia Fluor 525
FAB177JF525
Janelia Fluor 549
FAB177I
Janelia Fluor 646
FAB177J
Janelia Fluor 669
FAB177JF669
PE/Atto594
FAB177PEATT594
PE/Cy5.5
FAB177PECY55
PE/Cy7
FAB177PECY7
Phycoerythrin
FAB177P-025
Unconjugated
MAB177-100
mFluor Violet 450 SE
FAB177MFV450
mFluor Violet 500 SE
FAB177MFV500
mFluor Violet 610 SE
FAB177MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB177-100
Carrier Free
MAB177-SP
Carrier Free
MAB177-100
Carrier Free
MAB177-500
Carrier Free
FAB177P-025
Carrier Free
FAB177A-100
Carrier Free
FAB177A-025
Carrier Free
FAB177N-100
Carrier Free
FAB177N-025
Carrier Free
FAB177V-100UG
Carrier Free
FAB177U-100UG
Carrier Free
FAB177T-100UG
Carrier Free
FAB177S-100UG
Carrier Free
FAB177R-100UG
Carrier Free
FAB177G-100UG
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IL-17RA/IL-17R Antibody (133617) [Phycoerythrin] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human IL-17 R
Leu33-Trp320
Accession # Q96F46
Specificity
Detects human IL-17 R in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant mouse (rm) IL‑17 R, rmIL‑17B R, or recombinant human IL‑17B R is observed. In Western blots, no cross-reactivity with rmIL-17 R is observed
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
IL17RA
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB177P in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IL-17RA/IL-17R Antibody (133617) [Phycoerythrin]

  • CD217 antigen
  • CD217
  • Cdw217
  • CDw217interleukin 17 receptor
  • hIL-17R
  • IL-17 R
  • IL-17 RA
  • IL-17 receptor A
  • IL17RA
  • IL-17RA
  • IL-17RAMGC10262
  • IL17Rinterleukin-17 receptor A
  • interleukin 17 receptor A

Background

Interleukin 17 (also known as CTLA-8) is a T cell-expressed pleotropic cytokine. IL-17 binds to IL-17 receptor (IL-17 R) which shares no homology with any known family of receptors. While the expression of IL-17 is restricted to activated T cells, the IL-17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. Human IL-17 R is a 120 kDa, 866 amino acid (aa) type I membrane glycoprotein with a 293 aa extracellular domain, a 21 aa carboxy-proximal transmembrane domain, and a 525 aa cytoplasmic tail. Within the ECD, human IL-17 R shares 72% aa sequence identity with mouse and rat IL-17 R. The signaling events of IL-17 includes activation of NF-kappa B and JNK, and require TNF receptor-associated factors 6 (TRAF6) in the signaling pathway.

  1. Yao, Z. et al. (1997) Cytokine 9:794.
  2. Schwander, R. et al. (2000) J. Exp. Med. 191:1233.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for IL-17RA/IL-17R Antibody (FAB177P)(8)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: Flow Cytometry, Western Blot.


Filter By Application
Flow Cytometry
(7)
Western Blot
(1)
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Human
(8)
All Species
Showing Publications 1 - 8 of 8.
Publications using FAB177P Applications Species
BRB Pires, R Binato, GM Ferreira, S Corrêa, B Du Rocher, D Bulzico, S Crocamo, EC Dos Santos, LG Lima, E Abdelhay Twist1 Influences the Expression of Leading Members of the IL-17 Signaling Pathway in HER2-Positive Breast Cancer Cells International Journal of Molecular Sciences, 2021-11-10;22(22):. 2021-11-10 [PMID: 34830027] (Western Blot, Human) Western Blot Human
A Gatsiou, K Sopova, A Tselepis, K Stellos Interleukin-17A Triggers the Release of Platelet-Derived Factors Driving Vascular Endothelial Cells toward a Pro-Angiogenic State Cells, 2021-07-22;10(8):. 2021-07-22 [PMID: 34440624] (Flow Cytometry, Human) Flow Cytometry Human
E Ferretti, E Di Carlo, E Ognio, G Fraternali, A Corcione, B Belmonte, JL Ravetti, C Tripodo, D Ribatti, V Pistoia IL-25 dampens the growth of human germinal center-derived B-cell non Hodgkin Lymphoma by curtailing neoangiogenesis Oncoimmunology, 2017-11-27;7(3):e1397249. 2017-11-27 [PMID: 29399397] (Flow Cytometry, Human) Flow Cytometry Human
Ahn S, Edwards A, Singh S, Young S, Lessey B, Tayade C IL-17A Contributes to the Pathogenesis of Endometriosis by Triggering Proinflammatory Cytokines and Angiogenic Growth Factors. J Immunol, 2015-08-10;195(6):2591-600. 2015-08-10 [PMID: 26259585] (Flow Cytometry, Human) Flow Cytometry Human
Halwani , Rabih, Al-Kufaidy , Roua, Vazquez-Tello , Alejandr, Pureza , Mary Ang, BaHammam , Ahmed S, Al-Jahdali , Hamdan, Alnassar , Sami A, Hamid , Qutayba, Al-Muhsen , Saleh IL-17 Enhances Chemotaxis of Primary Human B Cells during Asthma. PLoS ONE, 2014-12-10;9(12):e114604. 2014-12-10 [PMID: 25494178] (Flow Cytometry, Human) Flow Cytometry Human
Dalmas E, Venteclef N, Caer C, Poitou C, Cremer I, Aron-Wisnewsky J, Lacroix-Desmazes S, Bayry J, Kaveri S, Clement K, Andre S, Guerre-Millo M T cell-derived IL-22 amplifies IL-1beta-driven inflammation in human adipose tissue: relevance to obesity and type 2 diabetes. Diabetes, 2014-02-11;63(6):1966-77. 2014-02-11 [PMID: 24520123] (Flow Cytometry, Human) Flow Cytometry Human
Chang Y, Al-Alwan L, Risse PA, Roussel L, Rousseau S, Halayko AJ, Martin JG, Hamid Q, Eidelman DH TH17 cytokines induce human airway smooth muscle cell migration. J. Allergy Clin. Immunol., 2011-02-22;127(4):1046-53.e1-2. 2011-02-22 [PMID: 21345484] (Flow Cytometry, Human) Flow Cytometry Human
Brucklacher-Waldert V, Steinbach K, Lioznov M, Kolster M, Holscher C, Tolosa E Phenotypical characterization of human Th17 cells unambiguously identified by surface IL-17A expression. J. Immunol., 2009-11-01;183(9):5494-501. 2009-11-01 [PMID: 19843935] (Flow Cytometry, Human) Flow Cytometry Human

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Bioinformatics

Gene Symbol IL17RA
Uniprot