Ikaros/IKZF1 Antibody (21E9) Summary
Additional Information |
Recombinant monoclonal antibody expressed in HEK293F cells |
Immunogen |
A synthesized peptide derived from Human Ikaros/IKZF1 [UniProt Q13422] |
Isotype |
IgG |
Clonality |
Monoclonal |
Host |
Rabbit |
Gene |
IKZF1 |
Purity |
Affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- ELISA
- Flow Cytometry 1:50-1:200
|
Packaging, Storage & Formulations
Storage |
Store at -20 to -70C. Avoid freeze-thaw cycles. |
Buffer |
PBS, pH 7.4, 150mM NaCl, and 50% glycerol |
Preservative |
0.02% Sodium Azide |
Purity |
Affinity purified |
Alternate Names for Ikaros/IKZF1 Antibody (21E9)
Background
Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Binds with higher affinity to gamma satellite A. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs)
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for Ikaros/IKZF1 Antibody (NBP3-26204) (0)
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